EIF5 and EIF1AY

Number of citations of the paper that reports this interaction (PubMedID 12569173)
28

Data Source:
HPRD (in vitro)

		EIF5	EIF1AY
Description		eukaryotic translation initiation factor 5	eukaryotic translation initiation factor 1A Y-linked
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Synapse	Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Translation Initiation Factor Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding GTP Binding Cadherin Binding Eukaryotic Initiation Factor EIF2 Binding	TRNA Binding RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translation Translational Initiation Regulation Of Translational Initiation Ribosome Assembly	Translation Translational Initiation
Pathways		Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Monocyte count ( 29403010) Number of sexual partners ( 30643258) Red blood cell traits ( 23222517)	Autism ( 32996047)
Interacting Genes		18 interacting genes: APP CDC42 CEBPA CSNK2A1 CSNK2B DUSP12 EIF1AX EIF1AY EIF2S2 EIF3D EIF3G EIF4G1 EIF4G2 HSPB1 NCBP2 NRGN OGT PUM1	4 interacting genes: ATXN1 EIF5 HNF4A SRPK2
Entrez ID		1983	9086
HPRD ID		03417	02455
Ensembl ID		ENSG00000100664	ENSG00000198692
Uniprot IDs		P55010	A6NJH9 O14602
PDB IDs		2E9H 2G2K 2IU1 8OZ0 8PJ2 8PJ3
Enriched GO Terms of Interacting Partners?		Translational Initiation Translation Initiation Factor Activity Cytoplasmic Translational Initiation Regulation Of Translational Initiation Translation Regulation Of Translation Translation Factor Activity, RNA Binding Cap-dependent Translational Initiation Post-transcriptional Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Cytosol RNA Binding Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Protein Metabolic Process Viral Translational Termination-reinitiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Metabolic Process Positive Regulation Of Cell Growth Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Eukaryotic Translation Initiation Factor 4F Complex Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Positive Regulation Of Growth MRNA Binding Regulation Of Synapse Organization Sin3-type Complex Translation Initiation Factor Binding Positive Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Catabolic Process Cellular Component Assembly Regulation Of Growth Regulation Of Presynapse Organization Regulation Of Presynapse Assembly PcG Protein Complex Post-transcriptional Gene Silencing Negative Regulation Of Proteolysis Viral Process	Protein-RNA Complex Assembly Eukaryotic Initiation Factor EIF2 Binding Regulation Of Ornithine Metabolic Process POZ Domain Binding Nuclear Speck Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?