LMTK2 and PPP1R2

Number of citations of the paper that reports this interaction (PMID 12393858)
16

Data Source:
HPRD (in vitro, in vivo)

		LMTK2	PPP1R2
Gene Name		lemur tyrosine kinase 2	protein phosphatase 1, regulatory (inhibitor) subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Golgi Apparatus Integral Component Of Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding	Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Receptor Recycling Protein Phosphorylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation	Glycogen Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 18264097)
Protein-Protein Interactions		5 interactors: CDK5 CDK5R1 PPP1CA PPP1CC PPP1R2	12 interactors: CDK5 CSNK2A1 CSNK2A2 GSK3B LMTK2 NEK2 PPP1CA PPP1CC PPP1R9A PPP1R9B TERF2IP TINF2
Entrez ID		22853	5504
HPRD ID		13994	03478
Ensembl ID		ENSG00000164715	ENSG00000184203
Uniprot IDs		Q8IWU2	P41236 Q6NXS2
PDB IDs
Enriched GO Terms of Interacting Partners?		Rhythmic Process Glycogen Metabolic Process Serine Phosphorylation Of STAT3 Protein Polysaccharide Metabolic Process Serine Phosphorylation Of STAT Protein Energy Reserve Metabolic Process Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Cellular Carbohydrate Metabolic Process Negative Regulation Of Axon Extension Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Positive Regulation Of Protein Targeting To Membrane Regulation Of Dendritic Spine Morphogenesis Energy Derivation By Oxidation Of Organic Compounds Regulation Of Signal Transduction Response To Light Stimulus Layer Formation In Cerebral Cortex Cerebral Cortex Radial Glia Guided Migration Peptidyl-threonine Phosphorylation Regulation Of Signaling Regulation Of Dendritic Spine Development Generation Of Precursor Metabolites And Energy Cell Division Positive Regulation Of Neuron Apoptotic Process Response To Radiation Cerebral Cortex Radially Oriented Cell Migration Negative Regulation Of Axonogenesis Glial Cell Migration Regulation Of Axon Extension Regulation Of Dendrite Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Hippocampus Development Positive Regulation Of Neuron Death Circadian Regulation Of Gene Expression Negative Regulation Of Developmental Growth Cerebral Cortex Cell Migration Regulation Of JAK-STAT Cascade Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Triglyceride Metabolic Process Regulation Of Circadian Rhythm Response To External Stimulus Limbic System Development Regulation Of Cell Cycle Arrest Positive Regulation Of Cell Death Negative Regulation Of Cell Morphogenesis Involved In Differentiation Telencephalon Cell Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Regulation Of Organelle Organization Cell Cycle Negative Regulation Of Chromosome Organization Rhythmic Process Regulation Of Mitotic Nuclear Division Regulation Of Cellular Component Organization Neuron Projection Development Regulation Of Cell Cycle Process Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Neuron Development Glycogen Metabolic Process Regulation Of Cell Division Neuron Differentiation Response To External Stimulus Negative Regulation Of Telomere Maintenance Polysaccharide Metabolic Process Regulation Of Chromosome Segregation Cell Projection Organization Phosphate-containing Compound Metabolic Process Protein Phosphorylation Regulation Of Cell Growth Regulation Of Signaling Peptidyl-serine Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Axon Guidance Cellular Protein Modification Process Regulation Of Telomere Maintenance Regulation Of Mitotic Cell Cycle Energy Reserve Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Division Negative Regulation Of Protein Metabolic Process Triglyceride Catabolic Process Generation Of Neurons Regulation Of Carbohydrate Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Entrainment Of Circadian Clock By Photoperiod Neurogenesis Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Circadian Rhythm Cell Cycle Process Protein Localization To Chromosome Axonogenesis Telomere Maintenance Via Telomere Lengthening Regulation Of Protein Export From Nucleus Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?			a375 abrogating augmentation benzodiazepines calyculin contrasted dephosphorylates fmk haematological hdac6 hdaci hybridizing hybrids hypophos mechanistically melanin melanocytes offering oxamflatin phorylated pig1 prompted prospects rising saha shuffling timp vad
Tagcloud (Difference) ?			a375 abrogating augmentation benzodiazepines calyculin contrasted dephosphorylates fmk haematological hdac6 hdaci hybridizing hybrids hypophos mechanistically melanin melanocytes offering oxamflatin phorylated pig1 prompted prospects rising saha shuffling timp vad
Tagcloud (Intersection) ?