FGFR1 and PIK3R1

  • Number of citations of the paper that reports this interaction (PMID 15117958)
  • 9
  • Data Source:
  • HPRD (in vivo, in vitro)

FGFR1

PIK3R1

Gene Name fibroblast growth factor receptor 1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease biomarkers ( 23419831)
  • Menarche (age at onset) ( 23599027)
Protein-Protein Interactions 45 interactors: BNIP2 CREBBP CRK CTPS2 EPHA4 ERBB3 FDPS FGF1 FGF17 FGF18 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FLRT3 FRS2 FRS3 GRB14 GRB2 IL17RD ITK KPNB1 MMP2 NCAM1 NCK1 NCK2 NEDD4 NRP1 PIK3R1 PIK3R2 PLCG1 PTK6 RPS6KA1 RPS6KA3 RTN3 SH3BP2 SHC1 SLA SOS1 TNS2 VAV1 149 interactors: ABL1 ADAM12 ADAMTS2 AGAP2 AKT1 ALK ANK3 ARAF ARHGAP1 ARHGAP17 ARHGAP32 AXL BCAR1 BRCA1 CBL CBLB CCL14 CD19 CD22 CD28 CD2AP CD3E CD4 CD40 CD5 CD7 CDC42 CDH2 CHRNA7 CRK CRKL CSF1R CSF2RA CTLA4 CTNNB1 CXCL2 CYP4A11 DLX2 DNM1 DOK1 EGFR EPHA2 EPOR ERAS ERBB2 ERBB3 ESR1 EZR FASLG FCGR2A FES FGFR1 FYN GAB1 GAB2 GAB3 GHR GRB2 GSK3B GSPT1 GTF2H1 HCK HCST HDAC1 HGS HOXA1 HRAS HTT IFNAR1 IGF1R IL13 IL1R1 IL1RAP IL2RB IL7R INPP4A INSR IRS1 IRS2 IRS4 ITSN1 JAK1 JAK2 JAK3 KHDRBS1 KIT LAT LCK LCP2 MAPK8 MET MME MST1R NFKBIA NTRK1 NTRK2 NUP85 PDGFRA PDGFRB PECAM1 PFN1 PIK3AP1 PIK3CA PIK3CB PIK3CD PPM1A PSEN1 PSMB5 PTK2 PTK2B PTPN11 PTPN6 RAC1 RASA1 RB1 RET RRAS2 SH3KBP1 SHB SHC1 SLC9A2 SOCS1 SOCS6 SOCS7 SRC SSTR2 SYK SYN1 TEC TEK TGFBR1 TGFBR2 TIE1 TLR2 TOM1L1 TRAT1 TSHR TTR TUB TUBA1B TUBG1 TYK2 TYRO3 VAV1 VAV3 WAS WASF3 WBP11 YWHAG
Entrez ID 2260 5295
HPRD ID 00634 01381
Ensembl ID ENSG00000077782 ENSG00000145675
Uniprot IDs P11362 P27986
PDB IDs 1AGW 1CVS 1EVT 1FGI 1FGK 1FQ9 1XR0 2CR3 2FGI 3C4F 3DPK 3GQI 3GQL 3JS2 3KRJ 3KRL 3KXX 3KY2 3OJV 3RHX 3TT0 4F63 4F64 4F65 1A0N 1AZG 1H9O 1PBW 1PHT 1PIC 1PKS 1PKT 2IUG 2IUH 2IUI 2RD0 2V1Y 3HHM 3HIZ 3I5R 3I5S 4A55
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abrogated  abrogation  acetic  antiproliferative  aromatic  arteriosclerosis  compete  dimerization  embedded  f32  former  heparan  heparin  heparinase  hs  hydroxyphenoxy  kd  microvessel  mimics  mitogenic  nonsulfated  nontoxic  outgrowth  polyanionic  proteoglycans  restenosis  rg  rings 
16q  1q  affymetrix  classic  clustering  clusters  cytoskeleton  distinguished  epithelium  fresh  frozen  golm1  gpr137b  hierarchical  ilc  lcis  lobular  mastectomy  microarrays  microdissected  obligate  personalize  precursor  prophylactic  supervised  transcriptomic  triplets  u133a  unsupervised 
Tagcloud (Difference) ?
abrogated  abrogation  acetic  antiproliferative  aromatic  arteriosclerosis  compete  dimerization  embedded  f32  former  heparan  heparin  heparinase  hs  hydroxyphenoxy  kd  microvessel  mimics  mitogenic  nonsulfated  nontoxic  outgrowth  polyanionic  proteoglycans  restenosis  rg  rings 
16q  1q  affymetrix  classic  clustering  clusters  cytoskeleton  distinguished  epithelium  fresh  frozen  golm1  gpr137b  hierarchical  ilc  lcis  lobular  mastectomy  microarrays  microdissected  obligate  personalize  precursor  prophylactic  supervised  transcriptomic  triplets  u133a  unsupervised 
Tagcloud (Intersection) ?