BCAT2

Description		branched chain amino acid transaminase 2
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Catalytic Activity Branched-chain-amino-acid Transaminase Activity Protein Binding Transaminase Activity Transferase Activity L-leucine-2-oxoglutarate Transaminase Activity L-valine-2-oxoglutarate Transaminase Activity L-isoleucine-2-oxoglutarate Transaminase Activity
	Biological Process	Isoleucine Metabolic Process L-isoleucine Catabolic Process L-leucine Metabolic Process Valine Metabolic Process Lipid Metabolic Process Amino Acid Biosynthetic Process Branched-chain Amino Acid Metabolic Process Branched-chain Amino Acid Biosynthetic Process Branched-chain Amino Acid Catabolic Process Regulation Of Hormone Levels Cellular Response To Leukemia Inhibitory Factor
Pathways		Branched-chain amino acid catabolism
Drugs		Pyridoxal phosphate Glutamic acid Leucine Isoleucine Pyridoxamine-5'-Phosphate N-[O-Phosphono-Pyridoxyl]-Isoleucine alpha-Ketoisovalerate
Diseases
GWAS		Long-term memory (delayed word recall task) ( 29970928) Resting metabolic rate ( 28476931) Serum metabolite levels ( 33031748)
Interacting Genes		5 interacting genes: ALDOA APP CREB3 PTGDS USP1
Entrez ID		587
HPRD ID		00217
Ensembl ID		ENSG00000105552
Uniprot IDs		B3KSI3 O15382
PDB IDs		1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HGX 2HHF 5BWR 5BWT 5BWU 5BWV 5BWW 5BWX 5CR5 5HNE 5I5S 5I5T 5I5U 5I5V 5I5W 5I5X 5I5Y 5I60 5MPR 6PRX
Enriched GO Terms of Interacting Partners?		Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Regulation Of Monocyte Chemotaxis Platelet Alpha Granule Lumen Protein Tetramerization Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Regulation Of Cellular Response To Stress Positive Regulation Of Error-prone Translesion Synthesis Positive Regulation Of Deacetylase Activity Cell Recognition Fructose-bisphosphate Aldolase Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Chemotaxis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Prostaglandin-D Synthase Activity Negative Regulation Of Male Germ Cell Proliferation Protein Homooligomerization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Chemotaxis Axon Midline Choice Point Recognition Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Male Germ Cell Proliferation Release From Viral Latency
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