RBM24 and POU2AF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM24	POU2AF1
Description		RNA binding motif protein 24	POU class 2 homeobox associating factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Pre-mRNA Intronic Binding MRNA CDS Binding Sequence-specific MRNA Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding POU Domain Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Endocardial Cushion Development MRNA Processing Regulation Of Translation DNA Damage Response RNA Splicing Regulation Of Myotube Differentiation Positive Regulation Of Myotube Differentiation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Myoblast Differentiation MRNA Stabilization MRNA Destabilization 3'-UTR-mediated MRNA Destabilization Positive Regulation Of Skeletal Muscle Fiber Differentiation Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Cytoplasmic Translation	Germinal Center B Cell Differentiation Humoral Immune Response Positive Regulation Of Interleukin-6 Production Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus
Pathways
Drugs
Diseases
GWAS		Glucose homeostasis traits ( 25524916) Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels ( 23823483) Pursuit maintenance gain ( 29064472)	Brain morphology (MOSTest) ( 32665545) Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Lymphocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)
Interacting Genes		8 interacting genes: C10orf55 CREBBP DAZAP2 DUX4L9 POU2AF1 RBFOX1 RBPMS UBQLN2	54 interacting genes: CCDC120 CIMIP2B DGCR6L FOXD2 GATA2 GPS2 GTF2H1 GTF2I HEMK1 HGS HOXC8 HOXC9 ITGB4 KLHL38 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 MEIS2 MSX2 NAB1 NDUFAF3 NOTCH1 OTX1 PAX8 PITX2 POGZ POU2F1 POU2F2 PTPN11 RAMAC RBM24 RHOXF2 ROR2 SCAND1 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK TBX6 TENT5B TFG TLX3 USP2 VGLL3 VPS37C YPEL3 ZNF414 ZNF581
Entrez ID		221662	5450
HPRD ID		15228	03126
Ensembl ID		ENSG00000112183	ENSG00000110777
Uniprot IDs		A8KAI7 B7Z6B4 B7Z6B7 Q9BX46	Q16633
PDB IDs			1CQT
Enriched GO Terms of Interacting Partners?		Transcription Coactivator Activity Cytoplasmic Stress Granule P53 Binding Protein Destabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Transcription Coregulator Activity Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity POU Domain Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome MRNA CDS Binding Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of G Protein-coupled Receptor Internalization MRF Binding	DNA-binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Pattern Specification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regionalization Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Serotonin Transport Positive Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Pyrimidine Nucleoside Transmembrane Transporter Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Intermediate Filament Anterior/posterior Pattern Specification Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Putrescine Transmembrane Transporter Activity Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Nephron Tubule Development Embryonic Morphogenesis Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Renal Tubule Development Kidney Epithelium Development Cell Surface Receptor Signaling Pathway Involved In Heart Development Embryonic Hindlimb Morphogenesis Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport
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