ZBTB9 and DYRK2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZBTB9	DYRK2
Gene Name		zinc finger and BTB domain containing 9	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex
	Molecular Function	DNA Binding Metal Ion Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Manganese Ion Binding Ubiquitin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Phosphorylation Cellular Response To DNA Damage Stimulus Smoothened Signaling Pathway Peptidyl-tyrosine Phosphorylation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Glycogen Biosynthetic Process Negative Regulation Of NFAT Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 21685187)
Protein-Protein Interactions		31 interactors: CAPN7 CHURC1 DTNB DYRK2 EHHADH EIF4E2 GTF2E1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 LASP1 MCM6 MDFI MORF4L1 MYBL2 NFKB1 NR3C1 PARP1 PIN1 PIN4 PPARG PPARGC1B TSR2 ZFP64 ZFY ZKSCAN5 ZNF23 ZNF407 ZNF408 ZZZ3	20 interactors: APP ATM DDB1 DYRK4 HIST2H2BE HIST3H3 IKZF1 KATNA1 KXD1 LZTS2 MDM2 NR1I2 RAD54B SIAH2 SP100 TERT UBC UBR5 WDR62 ZBTB9
Entrez ID		221504	8445
HPRD ID		15695	04606
Ensembl ID		ENSG00000213588
Uniprot IDs		Q96C00	Q92630
PDB IDs			3K2L 3KVW 4AZF
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Import Into Nucleus Regulation Of Cholesterol Transport Regulation Of Macrophage Derived Foam Cell Differentiation Intracellular Receptor Signaling Pathway Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Glucocorticoid Mediated Signaling Pathway Negative Regulation Of Interleukin-12 Biosynthetic Process Response To Diuretic Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleocytoplasmic Transport Regulation Of Lipid Storage Negative Regulation Of Gene Expression Regulation Of Cholesterol Transporter Activity	Telomere Maintenance Intracellular Receptor Signaling Pathway DNA Damage Response, Signal Transduction By P53 Class Mediator Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage DNA Metabolic Process Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Signal Transduction By P53 Class Mediator Cellular Response To DNA Damage Stimulus Regulation Of Wnt Signaling Pathway Cell Cycle Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Chromatin Organization Mitotic G1 DNA Damage Checkpoint Replicative Senescence Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Arrest Microtubule Severing Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Organelle Organization Positive Regulation Of Cell Cycle Cellular Protein Catabolic Process Protein Ubiquitination Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Repair Chromatin Modification Protein Modification By Small Protein Conjugation
Tagcloud ?			better clinicopathological closely december dual free grade histological hormone hundred ihc immunohistochemical involvement january lymph metastasis node predict predictive prognosis recurrence seventy specificity stage status surgery ten underwent
Tagcloud (Difference) ?			better clinicopathological closely december dual free grade histological hormone hundred ihc immunohistochemical involvement january lymph metastasis node predict predictive prognosis recurrence seventy specificity stage status surgery ten underwent
Tagcloud (Intersection) ?