ZBTB9 and ZFY

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZBTB9	ZFY
Description		zinc finger and BTB domain containing 9	zinc finger protein Y-linked
Image
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Ovarian Follicle Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Germ Cell Development Spermatogenesis Fertilization Post-embryonic Development Multicellular Organism Growth Positive Regulation Of Transcription By RNA Polymerase II Oocyte Development Homeostasis Of Number Of Cells Parental Behavior
Pathways
Drugs			3-Cyclohexyl-L-alanine Picolinic acid
Diseases
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease or systemic sclerosis ( 32024964) Diastolic blood pressure ( 27841878) Lung cancer ( 28604730)
Interacting Genes		47 interacting genes: CAPN7 CBX8 CDYL2 CHURC1 CIB4 CKS1B DTNB DYRK2 EHHADH EIF4E2 GTF2E1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 LASP1 MCM6 MDFI MORF4L1 MYBL2 NFKB1 NR3C1 PARP1 PIN1 PIN4 PPARG PPARGC1B SNIP1 SYTL4 TCEA2 TCEANC TSPYL1 TSR2 UBE2I ZBTB24 ZBTB26 ZBTB48 ZFP64 ZFY ZKSCAN5 ZNF23 ZNF407 ZNF408 ZNF417 ZNF71 ZZZ3	4 interacting genes: DMRT3 KAT14 L3MBTL2 ZBTB9
Entrez ID		221504	7544
HPRD ID		15695	02466
Ensembl ID		ENSG00000213588	ENSG00000067646
Uniprot IDs		A0A1U9X8U5 Q96C00	P08048
PDB IDs		9B9V	1KLR 1KLS 1XRZ 5ZNF 7ZNF
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding DNA Binding Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Metal Ion Binding Intermediate Filament Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Keratin Filament Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Histone H3K27me3 Reader Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Adipose Tissue Development Positive Regulation Of MiRNA Metabolic Process Parental Behavior Nucleoplasm Regulation Of SMAD Protein Signal Transduction DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process LIM Domain Binding Male Sex Differentiation Ventral Spinal Cord Interneuron Specification Histone H4K20me1 Reader Activity Histone H4K20me2 Reader Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Odontogenesis Of Dentin-containing Tooth ATAC Complex Ectoderm Development Regulation Of Odontogenesis Regulation Of Macromolecule Biosynthetic Process Histone Acetyltransferase Activity Regulation Of Primary Metabolic Process Regulation Of Gene Expression Neuron Fate Specification Sex Differentiation Transmission Of Nerve Impulse Adult Walking Behavior Walking Behavior Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Metabolic Process Regulation Of Embryonic Development Nucleus Adult Locomotory Behavior Regulation Of Animal Organ Morphogenesis Cell Fate Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Promoter-specific Chromatin Binding Stem Cell Proliferation
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