ZBTB9 and PPARGC1B

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZBTB9	PPARGC1B
Gene Name		zinc finger and BTB domain containing 9	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mitochondrion Mediator Complex
	Molecular Function	DNA Binding Metal Ion Binding	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Receptor Activator Activity AF-2 Domain Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Ossification Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Receptor Activity
Pathways			PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 21685187)	Obesity-related traits ( 23251661) Tanning ( 19340012)
Protein-Protein Interactions		31 interactors: CAPN7 CHURC1 DTNB DYRK2 EHHADH EIF4E2 GTF2E1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 LASP1 MCM6 MDFI MORF4L1 MYBL2 NFKB1 NR3C1 PARP1 PIN1 PIN4 PPARG PPARGC1B TSR2 ZFP64 ZFY ZKSCAN5 ZNF23 ZNF407 ZNF408 ZZZ3	13 interactors: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513
Entrez ID		221504	133522
HPRD ID		15695	10594
Ensembl ID		ENSG00000213588	ENSG00000155846
Uniprot IDs		Q96C00	B7ZM40 Q86YN6
PDB IDs			3SP6
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Import Into Nucleus Regulation Of Cholesterol Transport Regulation Of Macrophage Derived Foam Cell Differentiation Intracellular Receptor Signaling Pathway Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Glucocorticoid Mediated Signaling Pathway Negative Regulation Of Interleukin-12 Biosynthetic Process Response To Diuretic Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleocytoplasmic Transport Regulation Of Lipid Storage Negative Regulation Of Gene Expression Regulation Of Cholesterol Transporter Activity	Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Transcription, DNA-templated Cellular Response To Organic Cyclic Compound RNA Biosynthetic Process Gene Expression Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Lipid Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Response To Steroid Hormone DNA-templated Transcription, Initiation Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Lipid Metabolic Process Cellular Metabolic Process Mammary Gland Epithelium Development Cellular Response To Organic Substance Regulation Of Glucose Metabolic Process Uterus Development Regulation Of Fatty Acid Beta-oxidation Intracellular Estrogen Receptor Signaling Pathway
Tagcloud ?			17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Difference) ?			17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Intersection) ?