PPARGC1B and ZNF212

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PPARGC1B	ZNF212
Gene Name		peroxisome proliferator-activated receptor gamma, coactivator 1 beta	zinc finger protein 212
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mediator Complex	Nucleus
	Molecular Function	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Receptor Activator Activity AF-2 Domain Binding	DNA Binding Transcription Cofactor Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	Ossification Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Receptor Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Tanning ( 19340012)
Protein-Protein Interactions		13 interactors: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513	23 interactors: ATF3 ATF4 CREB3L2 CSK DPF2 DUSP6 FAM90A1 FHL2 GNL1 HBP1 LOC155060 NFKBIA NKX2-3 PPARGC1B PTP4A1 RND1 SAP30BP SF3A3 SUV39H2 ZNF3 ZNF331 ZNF408 ZZZ3
Entrez ID		133522	7988
HPRD ID		10594	03859
Ensembl ID		ENSG00000155846	ENSG00000170260
Uniprot IDs		B7ZM40 Q86YN6	B3KQE6 Q9UDV6
PDB IDs		3SP6
Enriched GO Terms of Interacting Partners?		Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Transcription, DNA-templated Cellular Response To Organic Cyclic Compound RNA Biosynthetic Process Gene Expression Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Lipid Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Response To Steroid Hormone DNA-templated Transcription, Initiation Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Lipid Metabolic Process Cellular Metabolic Process Mammary Gland Epithelium Development Cellular Response To Organic Substance Regulation Of Glucose Metabolic Process Uterus Development Regulation Of Fatty Acid Beta-oxidation Intracellular Estrogen Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Regulation Of Cellular Process Cellular Response To Stress Cellular Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Organic Substance Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Response To Unfolded Protein Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Endoplasmic Reticulum Stress Regulation Of Bone Resorption Signal Transduction Regulation Of Bone Remodeling Intracellular Receptor Signaling Pathway Trabecula Morphogenesis Signaling Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Chylomicron Remnant Clearance Post-embryonic Digestive Tract Morphogenesis Cellular Response To Stimulus Negative Regulation Of ERK1 And ERK2 Cascade Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway
Tagcloud ?		17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish	adenocarcinomas assisted ba barrett bas biologically consistently desorption dr5 electrophoresis erbb3 esophageal examples finger flight ihc interesting ionization klf6 lgi1 maldi mucosae spots tandem tof validated validation znf146 znf363
Tagcloud (Difference) ?		17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish	adenocarcinomas assisted ba barrett bas biologically consistently desorption dr5 electrophoresis erbb3 esophageal examples finger flight ihc interesting ionization klf6 lgi1 maldi mucosae spots tandem tof validated validation znf146 znf363
Tagcloud (Intersection) ?