PPARGC1B and ZNF513

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PPARGC1B	ZNF513
Gene Name		peroxisome proliferator-activated receptor gamma, coactivator 1 beta	zinc finger protein 513
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mediator Complex	Nucleus
	Molecular Function	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Receptor Activator Activity AF-2 Domain Binding	DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Ossification Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Receptor Activity	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Visual Perception Response To Stimulus Retina Development In Camera-type Eye
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Tanning ( 19340012)
Protein-Protein Interactions		13 interactors: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513	4 interactors: KAT5 PPARGC1B ZFP64 ZZZ3
Entrez ID		133522	130557
HPRD ID		10594	15813
Ensembl ID		ENSG00000155846	ENSG00000163795
Uniprot IDs		B7ZM40 Q86YN6	Q8N8E2
PDB IDs		3SP6
Enriched GO Terms of Interacting Partners?		Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Transcription, DNA-templated Cellular Response To Organic Cyclic Compound RNA Biosynthetic Process Gene Expression Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Lipid Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Response To Steroid Hormone DNA-templated Transcription, Initiation Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Lipid Metabolic Process Cellular Metabolic Process Mammary Gland Epithelium Development Cellular Response To Organic Substance Regulation Of Glucose Metabolic Process Uterus Development Regulation Of Fatty Acid Beta-oxidation Intracellular Estrogen Receptor Signaling Pathway	Intracellular Steroid Hormone Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Intracellular Receptor Signaling Pathway Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From Mitochondrial Promoter Regulation Of Gene Expression Bone Trabecula Formation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Response To Steroid Hormone Positive Regulation Of Alkaline Phosphatase Activity Positive Regulation Of Bone Resorption Nitrogen Compound Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Bone Trabecula Morphogenesis Cellular Response To Estradiol Stimulus Negative Regulation Of Interleukin-2 Production Positive Regulation Of Protein Acetylation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Estrogen Stimulus Positive Regulation Of Tissue Remodeling Chromatin Organization Positive Regulation Of Phosphatase Activity Regulation Of Bone Resorption Positive Regulation Of RNA Splicing Androgen Receptor Signaling Pathway Positive Regulation Of Receptor Activity Response To Lipid Regulation Of Bone Remodeling Response To Organic Cyclic Compound Positive Regulation Of Dephosphorylation Trabecula Morphogenesis Organelle Organization
Tagcloud ?		17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Difference) ?		17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Intersection) ?