CCDC89 and TSFM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC89	TSFM
Description		coiled-coil domain containing 89	Ts translation elongation factor, mitochondrial
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Mitochondrion Intracellular Organelle Lumen
	Molecular Function	Protein Binding	RNA Binding Translation Elongation Factor Activity Protein Binding
	Biological Process		Translation Translational Elongation Mitochondrial Translational Elongation
Pathways			Mitochondrial translation elongation
Drugs
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Age at first sexual intercourse ( 34211149) Refractive error ( 32231278)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 24076602)
Interacting Genes		5 interacting genes: BMPR2 FAM50B LRRC45 PIK3R3 TSFM	12 interacting genes: CCDC89 CDC42 CEP70 CPLX2 DRC4 GOLGA6L9 KRTAP1-1 LIG4 MDFI MTRNR2L1 PPP1R12C RALBP1
Entrez ID		220388	10102
HPRD ID		08234	05285
Ensembl ID		ENSG00000179071	ENSG00000123297
Uniprot IDs		Q8N998	E5KS95 P43897
PDB IDs		8WQA 8WQB 8WQD 8WQH	2CP9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis 1-phosphatidylinositol-3-kinase Regulator Activity Phosphatidylinositol 3-kinase Complex Mitochondrial Translational Elongation Maternal Placenta Development Lung Vasculature Development Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process 1-phosphatidylinositol-3-kinase Activity Phosphatidylinositol 3-kinase Complex, Class IA Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Intracellular Organelle Lumen Lymphangiogenesis Retina Vasculature Development In Camera-type Eye Regulation Of Axon Extension Involved In Axon Guidance Atrial Septum Morphogenesis
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