CCDC89 and FAM50B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC89	FAM50B
Description		coiled-coil domain containing 89	family with sequence similarity 50 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Midbody Intercellular Bridge
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Chromatin Organization
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Refractive error ( 32231278)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)
Interacting Genes		5 interacting genes: BMPR2 FAM50B LRRC45 PIK3R3 TSFM	49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1
Entrez ID		220388	26240
HPRD ID		08234	16883
Ensembl ID		ENSG00000179071	ENSG00000145945
Uniprot IDs		Q8N998	Q9Y247
PDB IDs		8WQA 8WQB 8WQD 8WQH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis 1-phosphatidylinositol-3-kinase Regulator Activity Phosphatidylinositol 3-kinase Complex Mitochondrial Translational Elongation Maternal Placenta Development Lung Vasculature Development Pharyngeal Arch Artery Morphogenesis Endothelial Cell Apoptotic Process 1-phosphatidylinositol-3-kinase Activity Phosphatidylinositol 3-kinase Complex, Class IA Transmembrane Receptor Protein Serine/threonine Kinase Activity Negative Regulation Of Vasoconstriction Endocardial Cushion Development Intracellular Organelle Lumen Lymphangiogenesis Retina Vasculature Development In Camera-type Eye Regulation Of Axon Extension Involved In Axon Guidance Atrial Septum Morphogenesis	Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Cytoskeleton Organelle Organization Cytoplasm Intracellular Protein Localization Protein Binding Protein Localization To Organelle Identical Protein Binding Nuclear Import Signal Receptor Activity Protein Transport Cellular Localization Intracellular Transport Spindle Organization Microtubule Organizing Center Organization Nuclear Pore Regulation Of Microtubule-based Process Centrosome Establishment Of Protein Localization Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Establishment Of Localization In Cell Telomere Localization Organelle Localization NLS-dependent Protein Nuclear Import Complex Protein Localization To Cytoskeleton Microtubule Microtubule Cytoskeleton Organization Involved In Mitosis Ubiquitin Protein Ligase Activity Spindle Midzone Assembly Cellular Component Assembly Protein Localization To Microtubule Microtubule Binding Positive Regulation Of Synaptic Transmission, GABAergic Enzyme Binding Negative Regulation Of Viral Transcription Membraneless Organelle Assembly Intermediate Filament Organization Regulation Of Microtubule Cytoskeleton Organization Transcription Coactivator Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Endocytic Recycling Regulation Of Viral Transcription Chromosome Localization Dynein Complex Binding Response To Muramyl Dipeptide
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