EVI2B and AQP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI2B	AQP3
Description		ecotropic viral integration site 2B	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Cell Cycle Myeloid Cell Development Regulation Of Stem Cell Division	Positive Regulation Of Immune System Process Response To Ischemia Renal Water Homeostasis Water Transport Glycerol Transmembrane Transport Urea Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Establishment Of Localization In Cell Transmembrane Transport Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs			Bisacodyl Sennosides
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		31 interacting genes: APOD AQP1 AQP3 BTN2A2 CDIPT CLN6 CNIH1 DESI1 DRAM1 FAM3C FUNDC2 GALNT15 GIMAP5 MYADML2 NINJ2 NSG1 PGRMC1 RTP2 SCAMP4 SLC2A5 SLC30A2 SLC38A7 SLC39A9 TMEM107 TMEM222 TMEM60 TMEM86B TRAF3IP3 TRAM1L1 UBIAD1 VAMP4	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		2124	360
HPRD ID		08867	08970
Ensembl ID		ENSG00000185862	ENSG00000165272
Uniprot IDs		P34910 Q9BRW1	A0A2R8Y2R4 B4E034 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Polyol Transmembrane Transport Renal Water Transport Renal Water Absorption Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Lysosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Water Channel Activity Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Protein Binding Renal Water Homeostasis Lysosomal Membrane Establishment Of Protein Localization To Membrane Golgi Apparatus Endoplasmic Reticulum Negative Regulation Of Lipoprotein Lipid Oxidation Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Multicellular Organismal-level Water Homeostasis One-carbon Compound Transport Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Water Transport Fructose Import Across Plasma Membrane Zinc Ion Import Into Zymogen Granule Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Trans-Golgi Network Membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Multivesicular Body Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity D-lysine 5,6-aminomutase Activity	Membrane
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