EVI2B and BTN2A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI2B	BTN2A2
Description		ecotropic viral integration site 2B	butyrophilin subfamily 2 member A2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Cell Cycle Myeloid Cell Development Regulation Of Stem Cell Division	G1/S Transition Of Mitotic Cell Cycle Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Regulatory T Cell Differentiation Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Liver iron content ( 34128465) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Smoking initiation ( 33082346) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		31 interacting genes: APOD AQP1 AQP3 BTN2A2 CDIPT CLN6 CNIH1 DESI1 DRAM1 FAM3C FUNDC2 GALNT15 GIMAP5 MYADML2 NINJ2 NSG1 PGRMC1 RTP2 SCAMP4 SLC2A5 SLC30A2 SLC38A7 SLC39A9 TMEM107 TMEM222 TMEM60 TMEM86B TRAF3IP3 TRAM1L1 UBIAD1 VAMP4	46 interacting genes: AQP6 ARL13B BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A1 SLC10A6 SLC14A1 SLC16A2 SLC18A1 SLC1A3 SLC30A4 SLC35H1 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2
Entrez ID		2124	10385
HPRD ID		08867	12545
Ensembl ID		ENSG00000185862	ENSG00000124508
Uniprot IDs		P34910 Q9BRW1	Q8WVV5
PDB IDs			8IH4
Enriched GO Terms of Interacting Partners?		Membrane Polyol Transmembrane Transport Renal Water Transport Renal Water Absorption Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Lysosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Water Channel Activity Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Protein Binding Renal Water Homeostasis Lysosomal Membrane Establishment Of Protein Localization To Membrane Golgi Apparatus Endoplasmic Reticulum Negative Regulation Of Lipoprotein Lipid Oxidation Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Multicellular Organismal-level Water Homeostasis One-carbon Compound Transport Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Water Transport Fructose Import Across Plasma Membrane Zinc Ion Import Into Zymogen Granule Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Trans-Golgi Network Membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Multivesicular Body Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity D-lysine 5,6-aminomutase Activity	Membrane Transmembrane Transport Protein Binding Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Neurotransmitter Transport
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