EVI2B and FAM3C

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		EVI2B	FAM3C
Name		ecotropic viral integration site 2B	FAM3 metabolism regulating signaling molecule C
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Cytokine Activity Protein Binding Carbohydrate Binding
	Biological Process	Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Cell Cycle Myeloid Cell Development Regulation Of Stem Cell Division	Inflammatory Response Epidermal Cell Differentiation Gene Expression Neutrophil Differentiation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Keratinocyte Proliferation ERK1 And ERK2 Cascade
Pathways		None	Platelet degranulation
GWAS		Brain morphology (MOSTest) ( 32665545 ) Oily fish consumption ( 32066663 ) Pork consumption ( 32066663 )	Biomedical quantitative traits ( 19396169 ) Bone mineral density (paediatric, lower limb) ( 24945404 ) Bone mineral density (paediatric, skull) ( 24945404 ) Bone mineral density (paediatric, total body less head) ( 24945404 ) Bone mineral density (paediatric, upper limb) ( 24945404 ) Calcaneus stiffness index ( 30779856 ) Forearm bone mineral density ( 26367794 ) Hand grip strength ( 27325353 ) Heel bone mineral density ( 28869591 30598549 ) Lung adenocarcinoma ( 28604730 ) Pediatric bone mineral content (radius) ( 26041818 ) Phenylephrine infusion rate during anesthesia ( 31455332 ) Total body bone mineral density ( 30172743 ) Ulna and radius bone mineral density ( 30172743 )
Interacting Genes		31 interacting genes: APOD AQP1 AQP3 BTN2A2 CDIPT CLN6 CNIH1 DESI1 DRAM1 FAM3C FUNDC2 GALNT15 GIMAP5 MYADML2 NINJ2 NSG1 PGRMC1 RTP2 SCAMP4 SLC2A5 SLC30A2 SLC38A7 SLC39A9 TMEM107 TMEM222 TMEM60 TMEM86B TRAF3IP3 TRAM1L1 UBIAD1 VAMP4	50 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GOLPH3 GOLPH3L GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		2124	10447
HPRD ID		08867	12270
Ensembl ID		ENSG00000185862	ENSG00000196937
Uniprot IDs		P34910 Q9BRW1	Q92520
PDB IDs		Not available	5LC2
GO Terms Enriched among Interactors		Membrane Polyol Transmembrane Transport Renal Water Transport Renal Water Absorption Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Lysosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Water Channel Activity Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Protein Binding Renal Water Homeostasis Lysosomal Membrane Establishment Of Protein Localization To Membrane Golgi Apparatus Endoplasmic Reticulum Negative Regulation Of Lipoprotein Lipid Oxidation Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Multicellular Organismal-level Water Homeostasis One-carbon Compound Transport Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Water Transport Fructose Import Across Plasma Membrane Zinc Ion Import Into Zymogen Granule Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Trans-Golgi Network Membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Multivesicular Body Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity D-lysine 5,6-aminomutase Activity	Membrane Protein Binding Protein Targeting To Golgi Apparatus Golgi Vesicle Budding Cargo Adaptor Activity