AQP3 and TMEM107

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AQP3	TMEM107
Description		aquaporin 3 (Gill blood group)	transmembrane protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane	Cilium Membrane Ciliary Transition Zone MKS Complex Cell Projection
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity Identical Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Immune System Process Response To Ischemia Renal Water Homeostasis Water Transport Glycerol Transmembrane Transport Urea Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Establishment Of Localization In Cell Transmembrane Transport Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport	Detection Of Nodal Flow Determination Of Left/right Symmetry Regulation Of Gene Expression Neural Tube Patterning Cell Projection Organization Embryonic Digit Morphogenesis Cilium Organization Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs		Bisacodyl Sennosides
Diseases
GWAS		Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)	Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)
Interacting Genes		28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN	45 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 CPLX4 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35H1 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21
Entrez ID		360	84314
HPRD ID		08970	14400
Ensembl ID		ENSG00000165272	ENSG00000179029
Uniprot IDs		A0A2R8Y2R4 B4E034 Q92482	E9PIH0 Q6UX40
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Monoatomic Ion Transport Metal Ion Transport Renal Water Transport
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