AQP3 and TMEM86A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AQP3	TMEM86A
Description		aquaporin 3 (Gill blood group)	transmembrane protein 86A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity Identical Protein Binding	Protein Binding Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity
	Biological Process	Positive Regulation Of Immune System Process Response To Ischemia Renal Water Homeostasis Water Transport Glycerol Transmembrane Transport Urea Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Establishment Of Localization In Cell Transmembrane Transport Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport	Lipid Metabolic Process
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs		Bisacodyl Sennosides
Diseases
GWAS		Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)	Ovarian reserve ( 22116950)
Interacting Genes		28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN	48 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 GPX8 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35H1 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP
Entrez ID		360	144110
HPRD ID		08970	08292
Ensembl ID		ENSG00000165272	ENSG00000151117
Uniprot IDs		A0A2R8Y2R4 B4E034 Q92482	Q8N2M4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Transmembrane Transport Protein Binding Connexin Complex Gap Junction Channel Activity Gap Junction Glycerol Transmembrane Transport Monoatomic Ion Transport Renal Water Transport Endoplasmic Reticulum Polyol Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Transport Vesicle Membrane
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