ETS1 and MAF

Number of citations of the paper that reports this interaction (PMID 9566892)
18

Data Source:
HPRD (in vitro)

		ETS1	MAF
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog 1	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Intercellular Bridge	Chromatin Nucleus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Sequence-specific DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding
	Biological Process	Response To Hypoxia Transcription From RNA Polymerase II Promoter Immune Response Female Pregnancy Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Positive Regulation Of Endothelial Cell Migration Regulation Of Extracellular Matrix Disassembly Hypothalamus Development Pituitary Gland Development PML Body Organization Response To Estradiol Response To Laminar Fluid Shear Stress Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Antibiotic Cell Motility Positive Regulation Of Cellular Component Movement Angiogenesis Involved In Wound Healing Cellular Response To Hydrogen Peroxide Response To Interleukin-1	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cytokine Production Transcription From RNA Polymerase II Promoter Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Inner Ear Development Lens Fiber Cell Differentiation
Pathways		Cellular Senescence Oncogene Induced Senescence
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Obesity-related traits ( 23251661) Rheumatoid arthritis ( 22446963) Systemic lupus erythematosus ( 23273568 20169177 19838193)	Height ( 20668459) Multiple sclerosis ( 21833088) Obesity ( 19151714) Renal function-related traits (urea) ( 22797727) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid volume ( 21565293) Urate levels ( 23263486)
Protein-Protein Interactions		47 interactors: APLP2 APP ARID4B ARL6IP4 ATF2 BRCA1 C17orf62 CAMK2A CAMK2B CREBBP DAXX EIF5B EP300 ETS2 FOS GATA3 HTATIP2 JUN MAF MAPK1 MAPK3 MAPK7 MED23 MEIS1 NCL NCOR1 NFKB1 NR3C1 PAX5 POU1F1 RBBP6 RFWD2 RPL13A RUNX1 RUNX1T1 RUNX2 SMAD3 SP1 SP100 SPI1 SRA1 SRC SRSF11 STAT5B STAT6 TDP2 UBE2I	15 interactors: ATF4 CREBBP EP300 ETS1 FOS FOSL1 HOXD12 JUN MAFA MAFB MAFG MYB SMARCA5 SOX9 USF2
Entrez ID		2113	4094
HPRD ID		01260	01518
Ensembl ID		ENSG00000134954	ENSG00000178573
Uniprot IDs		A8K725 B4DW78 P14921	O75444
PDB IDs		1GVJ 2NNY 2STT 2STW 3MFK 3RI4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Gene Expression RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Immune System Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Innate Immune Response Biosynthetic Process Developmental Process Cell Differentiation Cellular Metabolic Process Cellular Response To Organic Substance Immune Response Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Abiotic Stimulus Anatomical Structure Development Tissue Development Toll-like Receptor 5 Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Embryo Development Cellular Response To Extracellular Stimulus Response To Mechanical Stimulus Gland Development Positive Regulation Of Metabolic Process Response To Stress Multicellular Organismal Development N-terminal Peptidyl-lysine Acetylation Anatomical Structure Development Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Response To Abiotic Stimulus Response To Cytokine Cellular Metabolic Process Regulation Of Myeloid Cell Differentiation Response To Oxidative Stress Response To Organic Substance Developmental Process Response To Reactive Oxygen Species Regulation Of Immune System Process Response To Extracellular Stimulus
Tagcloud ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed	belongs chicken cnc conceivably consists dimeric disrupt erythroid erythroleukemia erythropoiesis exclusively globin integration kda lcrs leucine mast mega p45 pharmacologic polycythemia progenitors red retroviral substitute thrombocytopenia trilineage vera zipper
Tagcloud (Difference) ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed	belongs chicken cnc conceivably consists dimeric disrupt erythroid erythroleukemia erythropoiesis exclusively globin integration kda lcrs leucine mast mega p45 pharmacologic polycythemia progenitors red retroviral substitute thrombocytopenia trilineage vera zipper
Tagcloud (Intersection) ?