ETS1 and ARID4B

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		ETS1	ARID4B
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog 1	AT rich interactive domain 4B (RBP1-like)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Intercellular Bridge	Cellular_component Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Sequence-specific DNA Binding	Molecular_function Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Response To Hypoxia Transcription From RNA Polymerase II Promoter Immune Response Female Pregnancy Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Positive Regulation Of Endothelial Cell Migration Regulation Of Extracellular Matrix Disassembly Hypothalamus Development Pituitary Gland Development PML Body Organization Response To Estradiol Response To Laminar Fluid Shear Stress Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Antibiotic Cell Motility Positive Regulation Of Cellular Component Movement Angiogenesis Involved In Wound Healing Cellular Response To Hydrogen Peroxide Response To Interleukin-1	Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Spermatogenesis Biological_process Gene Expression Histone H4-K20 Trimethylation Histone H3-K9 Trimethylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Sertoli Cell Barrier
Pathways		Cellular Senescence Oncogene Induced Senescence	NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Obesity-related traits ( 23251661) Rheumatoid arthritis ( 22446963) Systemic lupus erythematosus ( 23273568 20169177 19838193)
Protein-Protein Interactions		47 interactors: APLP2 APP ARID4B ARL6IP4 ATF2 BRCA1 C17orf62 CAMK2A CAMK2B CREBBP DAXX EIF5B EP300 ETS2 FOS GATA3 HTATIP2 JUN MAF MAPK1 MAPK3 MAPK7 MED23 MEIS1 NCL NCOR1 NFKB1 NR3C1 PAX5 POU1F1 RBBP6 RFWD2 RPL13A RUNX1 RUNX1T1 RUNX2 SMAD3 SP1 SP100 SPI1 SRA1 SRC SRSF11 STAT5B STAT6 TDP2 UBE2I	4 interactors: ETS1 RANBP2 SAP130 SIN3A
Entrez ID		2113	51742
HPRD ID		01260	10661
Ensembl ID		ENSG00000134954	ENSG00000054267
Uniprot IDs		A8K725 B4DW78 P14921	Q4LE39
PDB IDs		1GVJ 2NNY 2STT 2STW 3MFK 3RI4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Gene Expression RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Immune System Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Innate Immune Response Biosynthetic Process Developmental Process Cell Differentiation Cellular Metabolic Process Cellular Response To Organic Substance Immune Response Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Abiotic Stimulus Anatomical Structure Development Tissue Development Toll-like Receptor 5 Signaling Pathway	Cellular Glucose Homeostasis Negative Regulation Of Gene Expression, Epigenetic RNA Biosynthetic Process Nucleus Organization Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Organelle Organization RNA Metabolic Process Cellular Response To Oxidative Stress Glucose Homeostasis Regulation Of Gene Expression, Epigenetic Gene Expression Positive Regulation Of Chromatin Silencing Macromolecule Biosynthetic Process Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Peptidyl-lysine Modification PML Body Organization Negative Regulation Of Glucokinase Activity Nucleobase-containing Compound Metabolic Process Histone Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Circadian Rhythm Response To Laminar Fluid Shear Stress Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Defense Response To Virus By Host Cellular Chemical Homeostasis Nitrogen Compound Metabolic Process Angiogenesis Involved In Wound Healing Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Histone Acetylation Wound Healing Chromatin Modification Regulation Of Gene Silencing Negative Regulation Of Peptidyl-lysine Acetylation Hypothalamus Development Negative Regulation Of Protein Acetylation Regulation Of Transcription Regulatory Region DNA Binding Protein Sumoylation Response To Organic Substance Cellular Homeostasis
Tagcloud ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed
Tagcloud (Difference) ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed
Tagcloud (Intersection) ?