AK4 and CEP19

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AK4	CEP19
Gene Name		adenylate kinase 4	centrosomal protein 19kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome	Spindle Pole Centriole Ciliary Basal Body
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding GTP Binding Nucleoside Triphosphate Adenylate Kinase Activity
	Biological Process	Liver Development Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process Brain Development Nucleoside Triphosphate Biosynthetic Process Response To Drug AMP Metabolic Process ATP Metabolic Process GTP Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP CEP19 EPHA8 KEAP1	13 interactors: AK4 CALCOCO1 CCDC102B CREB3L2 FGFR1OP KIAA1958 KXD1 RABL2A RABL2B REL SYNE4 VCP ZBTB14
Entrez ID		205	84984
HPRD ID		00048	17488
Ensembl ID		ENSG00000162433	ENSG00000174007
Uniprot IDs		P27144	Q96LK0
PDB IDs		2AR7 2BBW 3NDP
Enriched GO Terms of Interacting Partners?		Neuron Remodeling Neuron Maturation Cell Maturation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Proteasomal Ubiquitin-independent Protein Catabolic Process Positive Regulation Of Proteolysis Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Axon Guidance Positive Regulation Of Cellular Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Proteolysis Cellular Protein Modification Process Cell Morphogenesis Involved In Differentiation Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Activity MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Projection Morphogenesis Cell Part Morphogenesis Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Substrate-dependent Cell Migration Neuron Recognition Neuron Development Cellular Response To Interleukin-4 Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Epidermal Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Morphogenesis Regulation Of Cell Cycle G2/M Phase Transition Response To Interleukin-4 Cellular Protein Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Activity	Rab Protein Signal Transduction Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Establishment Of Epithelial Cell Apical/basal Polarity Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Cellular Protein Localization Regulation Of Protein Deubiquitination Cellular Localization Protein Hexamerization ADP Biosynthetic Process Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Transport Ras Protein Signal Transduction Establishment Of Monopolar Cell Polarity Aggresome Assembly Translesion Synthesis Nucleoside Diphosphate Biosynthetic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Golgi Vesicle Transport ADP Metabolic Process
Tagcloud ?		abolished adenocarcinoma adenylate advanced aggressive assist atf3 biomarkers invasion invasive limits lung mechanistically metastasis metastatic microarray overexpressing overexpression pivotal predicting promoted promotes promoting published recurrence simultaneous suppressed unfavorable upregulated
Tagcloud (Difference) ?		abolished adenocarcinoma adenylate advanced aggressive assist atf3 biomarkers invasion invasive limits lung mechanistically metastasis metastatic microarray overexpressing overexpression pivotal predicting promoted promotes promoting published recurrence simultaneous suppressed unfavorable upregulated
Tagcloud (Intersection) ?