AK4

Gene Name		adenylate kinase 4
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding GTP Binding Nucleoside Triphosphate Adenylate Kinase Activity
	Biological Process	Liver Development Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process Brain Development Nucleoside Triphosphate Biosynthetic Process Response To Drug AMP Metabolic Process ATP Metabolic Process GTP Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP CEP19 EPHA8 KEAP1
Entrez ID		205
HPRD ID		00048
Ensembl ID		ENSG00000162433
Uniprot IDs		P27144
PDB IDs		2AR7 2BBW 3NDP
Enriched GO Terms of Interacting Partners?		Neuron Remodeling Neuron Maturation Cell Maturation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Proteasomal Ubiquitin-independent Protein Catabolic Process Positive Regulation Of Proteolysis Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Axon Guidance Positive Regulation Of Cellular Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Proteolysis Cellular Protein Modification Process Cell Morphogenesis Involved In Differentiation Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Activity MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Projection Morphogenesis Cell Part Morphogenesis Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Substrate-dependent Cell Migration Neuron Recognition Neuron Development Cellular Response To Interleukin-4 Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Epidermal Cell Differentiation Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Morphogenesis Regulation Of Cell Cycle G2/M Phase Transition Response To Interleukin-4 Cellular Protein Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Activity
Tagcloud ?		abolished adenocarcinoma adenylate advanced aggressive assist atf3 biomarkers invasion invasive limits lung mechanistically metastasis metastatic microarray overexpressing overexpression pivotal predicting promoted promotes promoting published recurrence simultaneous suppressed unfavorable upregulated