EMX1 and ALX4

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		EMX1	ALX4
Gene Name		empty spiracles homeobox 1	ALX homeobox 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Transcription Factor Complex
	Molecular Function	Protein Binding Sequence-specific DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity HMG Box Domain Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Post-embryonic Development Cerebral Cortex Regionalization Cerebral Cortex Neuron Differentiation Response To Drug Brain Morphogenesis Neuron Projection Extension	Skeletal System Development Hair Follicle Development Transcription, DNA-templated Muscle Organ Development Post-embryonic Development Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Digit Morphogenesis Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Development Embryonic Skeletal System Morphogenesis Palate Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ALX4 ELK1 GTF2A1L HOXA10 POLR2D PRDM4 TP63	12 interactors: ALX1 CEBPE EMX1 FOXA3 GATA4 HOXA3 HOXB13 HOXB6 HOXD3 LEF1 SOX10 SOX2
Entrez ID		2016	60529
HPRD ID		08963	05661
Ensembl ID		ENSG00000135638	ENSG00000052850
Uniprot IDs		Q04741	Q9H161
PDB IDs			2M0C
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Embryonic Limb Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Limb Morphogenesis Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Limb Development Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Proximal/distal Pattern Formation Response To Gamma Radiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Pattern Specification Process Positive Regulation Of Transcription, DNA-templated Ectoderm And Mesoderm Interaction Epidermal Cell Division Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex Regulation Of Metabolic Process Hair Follicle Development Hair Cycle Process Skeletal System Development Hair Cycle Cellular Response To Testosterone Stimulus Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development MRNA Export From Nucleus In Response To Heat Stress Embryonic Morphogenesis Digestive Tract Development Cellular Response To Radiation Response To Ionizing Radiation Digestive System Development Regulation Of Epidermal Cell Division Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process	Organ Development Organ Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process System Development Embryonic Organ Development Anterior/posterior Pattern Specification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Multicellular Organismal Development Embryonic Organ Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Anatomical Structure Morphogenesis Gene Expression Embryonic Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Developmental Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Embryonic Skeletal System Morphogenesis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Embryonic Skeletal System Development Tube Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Mesenchyme Development Gland Development Morphogenesis Of An Epithelium Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Stem Cell Development
Tagcloud ?		124a accumulate annually appearing authentic cancers defect discontinued endoscopic endoscopy endpoint enrolled enrolment epigenetic excluding field gastric helicobacter metachronous multicentre nkx6 planned preselected pylori quartile takes trends undergone univariate	associating candidates cooccur cooperation crebbp driver exclusive forward foxr2 gli gli1 gnp gnps granule hedgehog medulloblastoma mutagenesis mutually nih3t3 oncogenes screen shh sonic strengthening subtype tended tgif2 transposon trp53
Tagcloud (Difference) ?		124a accumulate annually appearing authentic cancers defect discontinued endoscopic endoscopy endpoint enrolled enrolment epigenetic excluding field gastric helicobacter metachronous multicentre nkx6 planned preselected pylori quartile takes trends undergone univariate	associating candidates cooccur cooperation crebbp driver exclusive forward foxr2 gli gli1 gnp gnps granule hedgehog medulloblastoma mutagenesis mutually nih3t3 oncogenes screen shh sonic strengthening subtype tended tgif2 transposon trp53
Tagcloud (Intersection) ?