DR1 and NFIL3

Number of citations of the paper that reports this interaction (PMID 8836190)
10

Data Source:
HPRD (in vivo, in vitro)

		DR1	NFIL3
Gene Name		down-regulator of transcription 1, TBP-binding (negative cofactor 2)	nuclear factor, interleukin 3 regulated
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex	Nucleus
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Histone H3 Acetylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response Circadian Rhythm Positive Regulation Of Gene Expression Cellular Response To Interleukin-4
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		8 interactors: DRAP1 NFIL3 NFYC POLE3 TBP TTF2 XPO1 ZDHHC17	8 interactors: AMOTL2 BATF CREB3 DDIT3 DR1 MAFF MAFG TRAF2
Entrez ID		1810	4783
HPRD ID		03284	05619
Ensembl ID			ENSG00000165030
Uniprot IDs		Q01658 Q658N3	Q16649
PDB IDs		1JFI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Negative Regulation Of Cellular Metabolic Process DNA-templated Transcription, Termination Transcription, DNA-templated RNA Biosynthetic Process Pharynx Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Ribosomal Small Subunit Export From Nucleus Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Soft Palate Development Transcription From RNA Polymerase II Promoter Ribosomal Large Subunit Export From Nucleus Nitrogen Compound Metabolic Process Ribosomal Subunit Export From Nucleus Hard Palate Development Chromatin Silencing At RDNA Thyroid Hormone Generation Lipoprotein Transport Magnesium Ion Transport Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Export From Nucleus Termination Of RNA Polymerase I Transcription Thyroid Hormone Metabolic Process Transcription Elongation From RNA Polymerase I Promoter Thyroid Gland Development Intracellular Transport Of Virus Transcription Initiation From RNA Polymerase I Promoter Protein Palmitoylation Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase I Promoter	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Epidermal Cell Differentiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Response To Stress Gene Expression Regulation Of Epidermis Development Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Release From Viral Latency Regulation Of Transcription Involved In Anterior/posterior Axis Specification Response To Unfolded Protein Regulation Of Epithelial Cell Differentiation Cellular Response To Stress Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Heterocycle Metabolic Process T-helper 2 Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Aromatic Compound Metabolic Process Biosynthetic Process T-helper 17 Cell Lineage Commitment Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Deacetylase Activity Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction T-helper 17 Cell Differentiation Negative Regulation Of Glial Cell Apoptotic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Establishment Of Viral Latency ER Overload Response Response To Stimulus Positive Regulation Of Protein Homodimerization Activity Type 2 Immune Response Wnt Signaling Pathway
Tagcloud ?		cofactors conferred consensus cos cultured dr1d dr1p dr5 efficiently eighth harbors hcrabpii heterodimers heterologous homology insufficient kc keratinocytes nonfunctional rargamma responsiveness restored retinoid rxralpha share start supershift surprisingly	cardiomyoblast cardiomyocytes copyright correlates fibrosis h9c2 heart hearts hemorrhagic hypertrophy hypoxia hypoxic igf2 igf2r leucine luciferase mannose precipitation protected pull repress reserved rights stranded subjected superfamily suppresses triggers zipper
Tagcloud (Difference) ?		cofactors conferred consensus cos cultured dr1d dr1p dr5 efficiently eighth harbors hcrabpii heterodimers heterologous homology insufficient kc keratinocytes nonfunctional rargamma responsiveness restored retinoid rxralpha share start supershift surprisingly	cardiomyoblast cardiomyocytes copyright correlates fibrosis h9c2 heart hearts hemorrhagic hypertrophy hypoxia hypoxic igf2 igf2r leucine luciferase mannose precipitation protected pull repress reserved rights stranded subjected superfamily suppresses triggers zipper
Tagcloud (Intersection) ?