DCK and MED19

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DCK	MED19
Description		deoxycytidine kinase	mediator complex subunit 19
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Nucleotide Binding Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity Deoxyguanosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Deoxynucleoside Kinase Activity Protein Homodimerization Activity Cytidine Kinase Activity	Transcription Coregulator Activity Protein Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleotide Metabolic Process CMP Biosynthetic Process DAMP Salvage Carbohydrate Derivative Metabolic Process Nucleoside Phosphate Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		Pyrimidine salvage Purine salvage	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs		Fludarabine 2'-Deoxycytidine Elacytarabine
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 28991256 29483656)
Interacting Genes		7 interacting genes: ATM CRYAA DDX19B GOLM1 MED19 RXRG TFEC	19 interacting genes: APP DCK DHRS7B DTX2 GRB2 HLCS KANK2 MED17 MED27 MED31 MED8 MED9 MSX1 NEDD9 NFKBIA OSTF1 RADIL RIPPLY1 ZNF76
Entrez ID		1633	219541
HPRD ID		00507	17477
Ensembl ID		ENSG00000156136	ENSG00000156603
Uniprot IDs		B4E0A5 F5CTF3 P27707	A0JLT2 J3KR33
PDB IDs		1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLJ 4JLK 4JLM 4JLN 4KCG 4L5B 4Q18 4Q19 4Q1A 4Q1B 4Q1C 4Q1D 4Q1E 4Q1F 5MQJ 5MQL 5MQT 7ZI1 7ZI2 7ZI3 7ZI5 7ZI6 7ZI7 7ZI8 7ZI9 7ZIA 7ZIB 8OOJ	7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8TQW 8TRH
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Transcription Initiation By RNA Polymerase II Core Mediator Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Protein-DNA Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II Ubiquitin Ligase Complex Transcription Coregulator Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Ubiquitin Protein Ligase Activity Positive Regulation Of RNA Metabolic Process Regulation Of Dendritic Spine Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Post-translational Protein Modification Notch Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Ephrin Receptor Binding Protein Ubiquitination Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Macromolecule Biosynthetic Process Signal Transduction Involved In Regulation Of Gene Expression Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Lymphocyte Migration Nucleoplasm Guanyl-nucleotide Exchange Factor Adaptor Activity Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Negative Regulation Of Odontoblast Differentiation Acylglycerone-phosphate Reductase (NADP+) Activity Transcription Initiation At RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus
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