DCK and TFEC

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DCK	TFEC
Gene Name		deoxycytidine kinase	transcription factor EC
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Cytoplasm
	Molecular Function	Deoxycytidine Kinase Activity ATP Binding Drug Binding Nucleoside Kinase Activity Protein Homodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Purine Nucleobase Metabolic Process Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Phosphorylation Pyrimidine Nucleoside Salvage Purine-containing Compound Salvage Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To Heat Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Pyrimidine salvage reactions Purine metabolism Pyrimidine metabolism Metabolism of nucleotides Purine salvage
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DDX19B GOLM1 MED19 RXRG TFEC	8 interactors: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2
Entrez ID		1633	22797
HPRD ID		00507	05294
Ensembl ID		ENSG00000156136	ENSG00000105967
Uniprot IDs		F5CTF3 P27707	O14948
PDB IDs		1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLK 4L5B
Enriched GO Terms of Interacting Partners?			Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myeloid Cell Differentiation SNARE Complex Disassembly Humoral Immune Response Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Purine-containing Compound Salvage Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process
Tagcloud ?		affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Difference) ?		affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Intersection) ?