DCK and DDX19B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DCK	DDX19B
Gene Name		deoxycytidine kinase	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nuclear Envelope Nuclear Pore Cytoplasm Membrane Nuclear Membrane Extracellular Vesicular Exosome
	Molecular Function	Deoxycytidine Kinase Activity ATP Binding Drug Binding Nucleoside Kinase Activity Protein Homodimerization Activity	RNA Binding Helicase Activity ATP Binding
	Biological Process	Purine Nucleobase Metabolic Process Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Phosphorylation Pyrimidine Nucleoside Salvage Purine-containing Compound Salvage Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	MRNA Export From Nucleus Protein Transport
Pathways		Pyrimidine salvage reactions Purine metabolism Pyrimidine metabolism Metabolism of nucleotides Purine salvage
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DDX19B GOLM1 MED19 RXRG TFEC	13 interactors: APP B3GALT4 DCK GNB2L1 IKBKG MIF4GD NUP214 POT1 PRPSAP1 RWDD2B SKP1 TERF1 XPO7
Entrez ID		1633	11269
HPRD ID		00507	05781
Ensembl ID		ENSG00000156136	ENSG00000157349
Uniprot IDs		F5CTF3 P27707	B4DL69 Q9UMR2
PDB IDs		1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLK 4L5B	3EWS 3FHC 3FHT 3FMO 3FMP 3G0H
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Transferase Activity Regulation Of Telomerase Activity Negative Regulation Of Catalytic Activity Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Telomere Maintenance Via Telomere Lengthening Viral Process Protein Export From Nucleus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Proteolysis Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of DNA Strand Elongation Telomere Maintenance Regulation Of Kinase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Catabolic Process Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of CAMP Catabolic Process Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Telomere Formation Via Telomerase Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Mitotic Cell Cycle Nuclear Export MRNA Transport G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Shortening Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process RNA Transport
Tagcloud ?		affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying
Tagcloud (Difference) ?		affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying
Tagcloud (Intersection) ?