SLC2A8

Description		solute carrier family 2 member 8
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Fructose Transmembrane Transporter Activity D-glucose Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Response To Hypoxia Carbohydrate Metabolic Process Male Meiosis I Insulin Receptor Signaling Pathway Hexose Transmembrane Transport Fructose Transmembrane Transport Transmembrane Transport Dehydroascorbic Acid Transport D-glucose Transmembrane Transport
Pathways		Cellular hexose transport Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Major depressive disorder ( 27777418) Metabolite levels (HVA) ( 23319000)
Interacting Genes		4 interacting genes: AP1B1 AP2A2 AP2B1 BDKRB2
Entrez ID		29988
HPRD ID		05580
Ensembl ID		ENSG00000136856
Uniprot IDs		A0A087WT42 Q5VVV9 Q8WZ05 Q9NY64
PDB IDs
Enriched GO Terms of Interacting Partners?		Clathrin Adaptor Complex Membrane Coat Postsynaptic Neurotransmitter Receptor Internalization AP-2 Adaptor Complex Clathrin Adaptor Activity Endolysosome Membrane Clathrin-coated Endocytic Vesicle Clathrin-dependent Endocytosis Clathrin Binding Synaptic Vesicle Endocytosis Presynaptic Endocytosis Clathrin-coated Endocytic Vesicle Membrane Receptor Internalization Clathrin-coated Pit Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Secretion Endocytic Vesicle Membrane Intracellular Protein Transport Vesicle-mediated Transport In Synapse Cytoplasmic Side Of Plasma Membrane Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Synaptic Vesicle Cytoplasmic Vesicle Bradykinin Receptor Activity Kidney Development Receptor-mediated Endocytosis Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Protein Transport Signal Sequence Binding Vesicle-mediated Transport Basolateral Protein Secretion Extrinsic Component Of Presynaptic Endocytic Zone Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Type 1 Angiotensin Receptor Binding Intracellular Transport Endomembrane System Clathrin Coat Heart Development Establishment Of Protein Localization Postsynaptic Endocytic Zone Cellular Localization Establishment Of Localization In Cell Lysosomal Membrane AP-1 Adaptor Complex Secretion By Cell Regulation Of Cellular Response To Osmotic Stress Regulation Of Response To Osmotic Stress Endocytosis
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