MAP3K7CL and GPS2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		MAP3K7CL	GPS2
Gene Name		MAP3K7 C-terminal like	G protein pathway suppressor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Transcriptional Repressor Complex
	Molecular Function	Protein Binding	Transcription Corepressor Activity GTPase Inhibitor Activity Protein Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Inactivation Of MAPK Activity Chromatin Organization Cell Cycle JNK Cascade Negative Regulation Of JNK Cascade
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AK8 CISH GPS2 KRT31 REL TAB3	23 interactors: ATF4 C19orf57 CCNA1 CHD3 CNOT2 EP300 GOLGA2 HDAC1 HDAC3 KRT31 MAP3K7CL NCOR1 NR0B2 PBK RALBP1 RBPMS SESTD1 SETDB1 SPDL1 TBL1X TBL1XR1 TFIP11 TP53
Entrez ID		56911	2874
HPRD ID		10764	11878
Ensembl ID		ENSG00000156265	ENSG00000132522
Uniprot IDs		B0EVZ6 B0EVZ8 P57077	Q13227
PDB IDs			2L5G
Enriched GO Terms of Interacting Partners?		I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Protein Kinase Activity MAPK Cascade Negative Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Signaling Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Negative Regulation Of JAK-STAT Cascade Growth Hormone Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Growth Hormone Stimulus Negative Regulation Of JNK Cascade Phosphorylation Inactivation Of MAPK Activity Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Nucleoside Diphosphate Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Interleukin-12 Production Ventricular System Development	Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromosome Organization Transcription, DNA-templated Circadian Rhythm Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Rhythmic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Cellular Metabolic Process Circadian Regulation Of Gene Expression Regulation Of Gene Expression Histone Modification Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cell Cycle Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Organelle Organization Nucleobase-containing Compound Metabolic Process Histone H3-K9 Modification Regulation Of Metabolic Process Negative Regulation Of Stress-activated MAPK Cascade Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process
Tagcloud ?			abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Difference) ?			abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Intersection) ?