MAP3K7CL and USF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAP3K7CL	USF1
Description		MAP3K7 C-terminal like	upstream transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To UV Glucose Mediated Signaling Pathway Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis Cellular Response To Glucose Stimulus
Pathways			Estrogen-dependent gene expression Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases			Familial combined hyperlipidemia (FCHL)
GWAS		Alanine aminotransferase levels ( 33547301) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010 33339817) Ventricular ectopy ( 29618737) White blood cell count ( 32888494)	Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: AK8 CISH CRYAA DDIT4L GPS2 KRT31 KRT34 REL TAB3 USF1	20 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 HOMEZ LAP3 MAP3K7CL NFYA PLEKHF2 PPARGC1A PRKDC SNW1 TAOK2 TCF3 TCFL5 TRAF2 USF2
Entrez ID		56911	7391
HPRD ID		10764	01880
Ensembl ID		ENSG00000156265	ENSG00000158773
Uniprot IDs		B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077	A0A0S2Z4U5 P22415
PDB IDs			1AN4
Enriched GO Terms of Interacting Partners?		Structural Molecule Activity Non-canonical NF-kappaB Signal Transduction	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Chromatin Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Nucleoplasm Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of MiRNA Transcription Cellular Response To Oxygen-containing Compound Regulation Of MiRNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Transcription Regulator Complex Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex B Cell Lineage Commitment Regulation Of Developmental Process Regulation Of Primary Metabolic Process Mononuclear Cell Differentiation Leukocyte Activation Immunoglobulin V(D)J Recombination Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Leukocyte Differentiation Enzyme Binding Cell Activation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process RNA Metabolic Process DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Macromolecule Metabolic Process Regulation Of Multicellular Organismal Process Lymphocyte Activation Mitogen-activated Protein Kinase Kinase Kinase Binding Protein-containing Complex
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