FAM83A and FOXI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM83A	FOXI1
Description		family with sequence similarity 83 member A	forkhead box I1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Chromatin Nucleus Nucleolus
	Molecular Function	Protein Binding Protein Kinase Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Cell Population Proliferation White Fat Cell Differentiation Positive Regulation Of Adipose Tissue Development	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Signaling by EGFR
Drugs
Diseases			Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Urinary uromodulin levels ( 24578125)	Acne (severe) ( 24927181) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
Interacting Genes		23 interacting genes: BHLHE40 CYSRT1 DAZAP2 FOXH1 FOXI1 GCC1 GPSM1 KRT34 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MGAT5B NCK2 PLAGL2 PPP1R16B PRDM14 PSMA3 QARS1 SMYD1 TRIM23 TRIM27 UBASH3A	27 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX YAP1
Entrez ID		84985	2299
HPRD ID		17489	03057
Ensembl ID		ENSG00000147689	ENSG00000168269
Uniprot IDs		Q86UY5	E0XEN6 Q12951
PDB IDs		4URJ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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