HSCB and AGTRAP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HSCB	AGTRAP
Gene Name		HscB mitochondrial iron-sulfur cluster co-chaperone	angiotensin II receptor-associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Plasma Membrane	Golgi Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding Metal Ion Binding Chaperone Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Protein Folding Iron-sulfur Cluster Assembly Protein Oligomerization	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Esophageal cancer and gastric cancer ( 20729852)	Systolic blood pressure ( 19430483)
Protein-Protein Interactions		4 interactors: AGTRAP BBS1 BBS2 BBS4	70 interactors: ACSF2 ADCK3 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 BPIFA2 C12orf10 CAPNS1 CD160 CPLX1 CRCT1 DDA1 DDX55 DGCR6 FAM114A1 FAM160A2 FAM64A FARS2 FASTKD3 FATE1 GABARAPL2 GAD1 GAD2 GDNF GNB2L1 GTF3C1 HARS2 HIST1H4G HMGB1 HSCB HSPA4 ISCU KIAA0368 LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PITPNC1 PTPN9 RMDN2 SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TPD52L3 TUBA1B TXN2 ZFYVE21 ZNF391
Entrez ID		150274	57085
HPRD ID		16289	16379
Ensembl ID		ENSG00000100209	ENSG00000177674
Uniprot IDs		B0QYH2 Q8IWL3	Q6RW13
PDB IDs		3BVO
Enriched GO Terms of Interacting Partners?		Nonmotile Primary Cilium Assembly Photoreceptor Cell Maintenance Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Retina Homeostasis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Leptin-mediated Signaling Pathway Negative Regulation Of Appetite Cellular Response To Leptin Stimulus Cilium Assembly Visual Perception Sensory Perception Of Light Stimulus Regulation Of Microtubule-based Movement Tissue Homeostasis Cilium Organization Response To Leptin Striatum Development Cilium Morphogenesis Regulation Of Response To Food Multicellular Organismal Homeostasis Regulation Of Appetite Subpallium Development Golgi To Plasma Membrane Protein Transport Cell Projection Assembly Blood Circulation Golgi To Plasma Membrane Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Brain Morphogenesis Positive Regulation Of Multicellular Organism Growth Organelle Assembly Cellular Pigmentation Protein Localization To Organelle Hippocampus Development Establishment Of Protein Localization To Plasma Membrane Post-Golgi Vesicle-mediated Transport Limbic System Development Regulation Of Multicellular Organism Growth Pigmentation Sensory Perception Fat Cell Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Spermatid Development Spermatid Differentiation Protein Localization To Plasma Membrane Positive Regulation Of Developmental Growth Cerebral Cortex Development Adult Behavior	Succinate Metabolic Process Glutamate Decarboxylation To Succinate Glutamate Metabolic Process Iron-sulfur Cluster Assembly Renin-angiotensin Regulation Of Aldosterone Production Regulation Of Blood Vessel Size By Renin-angiotensin Dicarboxylic Acid Metabolic Process Glutamate Catabolic Process Angiotensin-activated Signaling Pathway Positive Regulation Of Oxidoreductase Activity Positive Regulation Of Protein Homooligomerization Positive Regulation Of Mitochondrial Fission Small Molecule Metabolic Process Negative Regulation Of Phagocytosis Regulation Of Mitochondrial Fission Regulation Of Blood Volume By Renin-angiotensin Dicarboxylic Acid Catabolic Process Neurotransmitter Biosynthetic Process Carboxylic Acid Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Protein Oligomerization Regulation Of Renal Sodium Excretion Regulation Of Branching Involved In Ureteric Bud Morphogenesis Carboxylic Acid Catabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Organic Acid Metabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Excretion Exploration Behavior Regulation Of Protein Oligomerization Neurotransmitter Metabolic Process Neurotransmitter Secretion Mitochondrion Organization Ornithine Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Succinyl-CoA Pathway Posterior Compartment Specification Anterior Compartment Pattern Formation Aldosterone Secretion Nitrogen Fixation Vasodilation By Angiotensin Involved In Regulation Of Systemic Arterial Blood Pressure L-methylmalonyl-CoA Metabolic Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Protein Targeting To Membrane Metanephros Morphogenesis Cellular Amino Acid Catabolic Process Cardiac Muscle Tissue Growth Biosynthetic Process
Tagcloud ?		acetylserine azotobacter bear cluster cyse designated desulfurization fdx hemophilus homodimer hsca hscba influenzae isca iscs iscsua iscu microsequencing nif nifs nifu nitrogenase oligopeptides orf6 proposal pyridoxal sulfur tryptic vinelandii	adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Difference) ?		acetylserine azotobacter bear cluster cyse designated desulfurization fdx hemophilus homodimer hsca hscba influenzae isca iscs iscsua iscu microsequencing nif nifs nifu nitrogenase oligopeptides orf6 proposal pyridoxal sulfur tryptic vinelandii	adrenal alpha1 apelin apln covers ephx2 epoxide genesis gja1 glands hydrolase hypertensive isolating kynu kynureninase kyoto normotensive osteonectin prone rgs2 rising shr shrsp sparc spock2 substrains urotensin uts2 wky
Tagcloud (Intersection) ?