CLDN19 and MS4A14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN19	MS4A14
Description		claudin 19	membrane spanning 4-domains A14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Cell Junction Paranodal Junction Schmidt-Lanterman Incisure Apical Junction Complex Perinuclear Region Of Cytoplasm Tight Junction Anchoring Junction Mesaxon	Plasma Membrane Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding Cell-cell Adhesion Mediator Activity Paracellular Tight Junction Channel Activity	Protein Binding
	Biological Process	Retinal Pigment Epithelium Development Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Cell Junction Assembly Apical Junction Assembly Renal Absorption Bicellular Tight Junction Assembly Tight Junction Organization Regulation Of Transepithelial Transport Paracellular Transport	Cell Surface Receptor Signaling Pathway
Pathways		Tight junction interactions
Drugs
Diseases
GWAS			Monocyte count ( 32888494) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35H1 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	6 interacting genes: CDIPT CLDN19 GIMAP5 SEC22A TMEM54 TMEM86B
Entrez ID		149461	84689
HPRD ID		10834	14863
Ensembl ID		ENSG00000164007	ENSG00000166928
Uniprot IDs		Q8N6F1	A0A0A0MS57 Q96JA4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding External Side Of Plasma Membrane Plasma Membrane	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Alcohol Binding Mesaxon D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Regulation Of Transepithelial Transport Phosphotransferase Activity, For Other Substituted Phosphate Groups Glycerophospholipid Metabolic Process Mitotic Nuclear Division Apical Junction Assembly Schmidt-Lanterman Incisure Paracellular Tight Junction Channel Activity Action Potential Propagation Retinal Pigment Epithelium Development Paracellular Transport Paranodal Junction Neuronal Action Potential Propagation CDP-diacylglycerol Metabolic Process Diacylglycerol Binding Phosphatidylcholine Acyl-chain Remodeling Endoplasmic Reticulum Membrane Glycerolipid Metabolic Process
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