PHF13 and CPTP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PHF13	CPTP
Description		PHD finger protein 13	ceramide-1-phosphate transfer protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nuclear Outer Membrane Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K9me2/3 Reader Activity Chromatin-protein Adaptor Activity	Phospholipid Binding Lipid Binding Lipid Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Mitotic Cell Cycle Chromatin Organization DNA Damage Response Chromosome Segregation Mitotic Chromosome Condensation Chromosome Condensation Cell Division	Lipid Transport Negative Regulation Of Autophagy Negative Regulation Of Interleukin-1 Beta Production Ceramide Transport Glycolipid Transport Intermembrane Lipid Transfer Negative Regulation Of NLRP3 Inflammasome Complex Assembly Ceramide 1-phosphate Transport
Pathways			Glycosphingolipid transport
Drugs
Diseases
GWAS		FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Peak expiratory flow ( 30804560)
Interacting Genes		2 interacting genes: CPTP TRIM28	7 interacting genes: CD7 ECM1 ELOC INPP5K PHF13 SMAD3 ZNF451
Entrez ID		148479	80772
HPRD ID		10150	18878
Ensembl ID		ENSG00000116273	ENSG00000224051
Uniprot IDs		A0A158RFV6 Q86YI8	Q5TA50 S4S694
PDB IDs		3O70 3O7A	4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?		Convergent Extension Involved In Axis Elongation Ubiquitin-like Protein Ligase Activity Krueppel-associated Box Domain Binding Embryonic Placenta Morphogenesis Chromo Shadow Domain Binding Ceramide 1-phosphate Transport Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity Glycolipid Transport Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Convergent Extension Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Lipid Transfer Activity Suppression Of Viral Release By Host Ceramide Transport Negative Regulation Of NLRP3 Inflammasome Complex Assembly SUMO Transferase Activity Genomic Imprinting Epigenetic Programming Of Gene Expression Positive Regulation Of Protein Import Into Nucleus DNA Methylation-dependent Constitutive Heterochromatin Formation Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-1 Production Negative Regulation Of Interleukin-1 Beta Production Intermembrane Lipid Transfer Nuclear Outer Membrane Embryo Implantation Negative Regulation Of Viral Genome Replication Regulation Of NLRP3 Inflammasome Complex Assembly Protein Sumoylation Heterochromatin Constitutive Heterochromatin Formation Euchromatin Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport	Regulation Of Bone Mineralization Negative Regulation Of Ossification Transcription Corepressor Binding Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Renal Water Transport Phosphatidylinositol Trisphosphate Phosphatase Activity Positive Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Ossification Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Interleukin-2 Receptor Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Sterol Response Element Binding Carbohydrate Homeostasis Transdifferentiation Glucose Homeostasis Positive Regulation Of Transforming Growth Factor Beta3 Production SMAD Protein Complex Pericardium Development DEAD/H-box RNA Helicase Binding Regulation Of Lung Blood Pressure Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Paraxial Mesoderm Morphogenesis Mesoderm Morphogenesis Heteromeric SMAD Protein Complex Regulation Of Stress Fiber Assembly Trophoblast Cell Migration Immune System Development Regulation Of Transforming Growth Factor Beta2 Production Target-directed MiRNA Degradation Elongin Complex Negative Regulation Of Transcription Initiation By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Initiation Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Bisphosphate Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Negative Regulation Of Dephosphorylation Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Vasopressin Receptor Activity Negative Regulation Of Protein Targeting To Membrane Interleukin-2-mediated Signaling Pathway Regulation Of Immune Response
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