PHF13

Description		PHD finger protein 13
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GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K9me2/3 Reader Activity Chromatin-protein Adaptor Activity
	Biological Process	Mitotic Cell Cycle Chromatin Organization DNA Damage Response Chromosome Segregation Mitotic Chromosome Condensation Chromosome Condensation Cell Division
Pathways
Drugs
Diseases
GWAS		FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Peak expiratory flow ( 30804560)
Interacting Genes		2 interacting genes: CPTP TRIM28
Entrez ID		148479
HPRD ID		10150
Ensembl ID		ENSG00000116273
Uniprot IDs		A0A158RFV6 Q86YI8
PDB IDs		3O70 3O7A
Enriched GO Terms of Interacting Partners?		Convergent Extension Involved In Axis Elongation Ubiquitin-like Protein Ligase Activity Krueppel-associated Box Domain Binding Embryonic Placenta Morphogenesis Chromo Shadow Domain Binding Ceramide 1-phosphate Transport Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity Glycolipid Transport Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Convergent Extension Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Lipid Transfer Activity Suppression Of Viral Release By Host Ceramide Transport Negative Regulation Of NLRP3 Inflammasome Complex Assembly SUMO Transferase Activity Genomic Imprinting Epigenetic Programming Of Gene Expression Positive Regulation Of Protein Import Into Nucleus DNA Methylation-dependent Constitutive Heterochromatin Formation Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-1 Production Negative Regulation Of Interleukin-1 Beta Production Intermembrane Lipid Transfer Nuclear Outer Membrane Embryo Implantation Negative Regulation Of Viral Genome Replication Regulation Of NLRP3 Inflammasome Complex Assembly Protein Sumoylation Heterochromatin Constitutive Heterochromatin Formation Euchromatin Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport
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