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CREB3L4 and GANAB
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
CREB3L4
GANAB
Gene Name
cAMP responsive element binding protein 3-like 4
glucosidase, alpha; neutral AB
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Integral Component Of Membrane
Endoplasmic Reticulum Lumen
Golgi Apparatus
Membrane
Glucosidase II Complex
Melanosome
Extracellular Vesicular Exosome
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
CAMP Response Element Binding
Carbohydrate Binding
Glucan 1,3-alpha-glucosidase Activity
Poly(A) RNA Binding
Biological Process
Transcription, DNA-templated
Spermatogenesis
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Folding
Protein N-linked Glycosylation Via Asparagine
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Defective ALG2 causes ALG2-CDG (CDG-1i)
Diseases of glycosylation
Defective ALG3 causes ALG3-CDG (CDG-1d)
Post-translational protein modification
Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Defective ALG1 causes ALG1-CDG (CDG-1k)
Defective MGAT2 causes MGAT2-CDG (CDG-2a)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective ALG6 causes ALG6-CDG (CDG-1c)
Defective MOGS causes MOGS-CDG (CDG-2b)
Defective RFT1 causes RFT1-CDG (CDG-1n)
Asparagine N-linked glycosylation
Defective ALG8 causes ALG8-CDG (CDG-1h)
Defective ALG9 causes ALG9-CDG (CDG-1l)
Defective MAN1B1 causes MRT15
Defective MPDU1 causes MPDU1-CDG (CDG-1f)
Defective ALG12 causes ALG12-CDG (CDG-1g)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Defective ALG11 causes ALG11-CDG (CDG-1p)
Diseases associated with N-glycosylation of proteins
Calnexin/calreticulin cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
GANAB
LRRC4C
SLC19A3
SOX9
7 interactors:
CCNH
CREB3L4
MAPK8
PRKCSH
PRRC2A
PTPRC
RAP1A
Entrez ID
148327
23193
HPRD ID
06323
03516
Ensembl ID
ENSG00000143578
ENSG00000089597
Uniprot IDs
Q8TEY5
B4DIW2
B4DSM6
B4DZ53
E9PKU7
F5H6X6
Q14697
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Proliferation Involved In Tissue Homeostasis
Epithelial Cell Proliferation Involved In Prostatic Bud Elongation
Retinal Rod Cell Differentiation
Primary Prostatic Bud Elongation
Male Germ-line Sex Determination
Renal Vesicle Induction
Thiamine Transmembrane Transport
Primary Sex Determination
Astrocyte Fate Commitment
Positive Regulation Of Extracellular Matrix Assembly
Thiamine Transport
Metanephric Nephron Tubule Formation
Intestinal Epithelial Structure Maintenance
Intrahepatic Bile Duct Development
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Negative Regulation Of Photoreceptor Cell Differentiation
Cellular Response To Heparin
Regulation Of Extracellular Matrix Assembly
Ureter Urothelium Development
Response To Heparin
Ureter Morphogenesis
Ureter Smooth Muscle Cell Differentiation
Chondrocyte Hypertrophy
Metanephric Tubule Formation
Regulation Of Mesenchymal Stem Cell Differentiation
Thiamine-containing Compound Metabolic Process
Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Common Bile Duct Development
Metanephric Nephron Tubule Morphogenesis
Limb Bud Formation
Otic Vesicle Formation
Pyrimidine-containing Compound Transmembrane Transport
Positive Regulation Of Male Gonad Development
Otic Vesicle Morphogenesis
Regulation Of Branching Involved In Lung Morphogenesis
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Metanephric Tubule Morphogenesis
Camera-type Eye Photoreceptor Cell Differentiation
Male Sex Determination
Maintenance Of Gastrointestinal Epithelium
Otic Vesicle Development
Ureter Development
ERK1 And ERK2 Cascade
Vitamin Transmembrane Transport
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Heart Valve Formation
Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
Metanephric Nephron Tubule Development
Regulation Of Neuron Differentiation
Response To Stress
Positive Regulation Of Metabolic Process
Cellular Response To Stimulus
Immunoglobulin Biosynthetic Process
Positive Regulation Of Hematopoietic Stem Cell Migration
Regulation Of Protein Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
JUN Phosphorylation
Neurotrophin Signaling Pathway
Regulation Of Catalytic Activity
Positive Regulation Of Deacetylase Activity
Negative Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Protein Phosphorylation
Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Positive Regulation Of Isotype Switching To IgG Isotypes
Bone Marrow Development
Response To Stimulus
Positive Regulation Of Cellular Metabolic Process
Cell Cycle Phase Transition
Positive Regulation Of Determination Of Dorsal Identity
Activation Of Protein Kinase Activity
Positive Regulation Of Gamma-delta T Cell Differentiation
N-glycan Processing
Rap Protein Signal Transduction
Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration
Regulation Of Isotype Switching To IgG Isotypes
Positive Thymic T Cell Selection
Signal Transduction
Positive Regulation Of Signal Transduction
Positive Regulation Of Gamma-delta T Cell Activation
Regulation Of Phosphorylation
Negative Regulation Of Protein Autophosphorylation
Positive Regulation Of Vasculogenesis
Defense Response
Cellular Response To Nitric Oxide
Nerve Growth Factor Signaling Pathway
Regulation Of Gamma-delta T Cell Differentiation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Negative Regulation Of T Cell Mediated Immunity
Negative Thymic T Cell Selection
Signaling
Regulation Of Neuron Projection Development
Negative Regulation Of Synaptic Vesicle Exocytosis
Negative T Cell Selection
Response To Nitric Oxide
Positive Regulation Of Alpha-beta T Cell Proliferation
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