CREB3L4 and SLC19A3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CREB3L4	SLC19A3
Description		cAMP responsive element binding protein 3 like 4	solute carrier family 19 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Nuclear Membrane	Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Thiamine Transmembrane Transporter Activity Vitamin Transmembrane Transporter Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Unfolded Protein Spermatogenesis Positive Regulation Of Transcription By RNA Polymerase II	Thiamine Diphosphate Biosynthetic Process Thiamine Transport Pyridoxine Transport Thiamine-containing Compound Metabolic Process Vitamin Transport Transmembrane Transport Thiamine Transmembrane Transport
Pathways		CREB3 factors activate genes	Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Blood protein levels ( 30072576) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: GANAB GET3 LRRC4C SLC19A3 SOX9	15 interacting genes: ARLN C3orf38 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1
Entrez ID		148327	80704
HPRD ID		06323	07311
Ensembl ID		ENSG00000143578	ENSG00000135917
Uniprot IDs		Q8TEY5	A0A2R8YHG5 Q9BZV2
PDB IDs			8S4U 8S5U 8S5W 8S5Z 8S61 8S62 8XV2 8XV5 8XV9 8Z7R 8Z7S 8Z7T 8Z7U 8Z7V 8Z7W 8Z7X 8Z7Y 9G5K
Enriched GO Terms of Interacting Partners?		Neural Crest Cell Fate Specification Male Germ-line Sex Determination Negative Regulation Of Beta-catenin-TCF Complex Assembly Bronchus Cartilage Development Ureter Urothelium Development Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Regulation Of Cell Proliferation Involved In Tissue Homeostasis Ureter Smooth Muscle Cell Differentiation Lung Smooth Muscle Development Intrahepatic Bile Duct Development Glc2Man9GlcNAc2 Oligosaccharide Glucosidase Activity Glucan 1,3-alpha-glucosidase Activity Glucosidase II Complex Pyridoxine Transport GET Complex Metanephric Tubule Formation Stem Cell Fate Specification Renal Vesicle Induction Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal Stem Cell Differentiation Chondrocyte Hypertrophy Cell Proliferation Involved In Heart Morphogenesis Trachea Cartilage Development Response To Heparin Prostate Gland Morphogenesis Cellular Response To Heparin Anterior Head Development Primary Sex Determination Harderian Gland Development Astrocyte Fate Commitment Common Bile Duct Development Growth Plate Cartilage Chondrocyte Growth Alpha-glucosidase Activity Thiamine Transmembrane Transporter Activity Thiamine Transport Thiamine Diphosphate Metabolic Process Thiamine Diphosphate Biosynthetic Process Thiamine Transmembrane Transport Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Branching Involved In Lung Morphogenesis Endochondral Bone Morphogenesis Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Lacrimal Gland Development Vitamin Transmembrane Transporter Activity Thiamine-containing Compound Metabolic Process Ureter Development Otic Vesicle Formation Ureter Morphogenesis Glial Cell Fate Specification Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
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