CREB3L4 and SLC19A3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CREB3L4	SLC19A3
Gene Name		cAMP responsive element binding protein 3-like 4	solute carrier family 19 (thiamine transporter), member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription CAMP Response Element Binding	Thiamine Uptake Transmembrane Transporter Activity
	Biological Process	Transcription, DNA-templated Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Thiamine-containing Compound Metabolic Process Small Molecule Metabolic Process Thiamine Transmembrane Transport
Pathways			Metabolism of vitamins and cofactors Defective GIF causes intrinsic factor deficiency Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Vitamin B1 (thiamin) metabolism Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs			L-Cysteine
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: GANAB LRRC4C SLC19A3 SOX9	3 interactors: C3orf38 CREB3L4 TAB2
Entrez ID		148327	80704
HPRD ID		06323	07311
Ensembl ID		ENSG00000143578	ENSG00000135917
Uniprot IDs		Q8TEY5	F5H2M8 Q9BZV2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Proliferation Involved In Tissue Homeostasis Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Retinal Rod Cell Differentiation Primary Prostatic Bud Elongation Male Germ-line Sex Determination Renal Vesicle Induction Thiamine Transmembrane Transport Primary Sex Determination Astrocyte Fate Commitment Positive Regulation Of Extracellular Matrix Assembly Thiamine Transport Metanephric Nephron Tubule Formation Intestinal Epithelial Structure Maintenance Intrahepatic Bile Duct Development Positive Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Photoreceptor Cell Differentiation Cellular Response To Heparin Regulation Of Extracellular Matrix Assembly Ureter Urothelium Development Response To Heparin Ureter Morphogenesis Ureter Smooth Muscle Cell Differentiation Chondrocyte Hypertrophy Metanephric Tubule Formation Regulation Of Mesenchymal Stem Cell Differentiation Thiamine-containing Compound Metabolic Process Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Limb Bud Formation Otic Vesicle Formation Pyrimidine-containing Compound Transmembrane Transport Positive Regulation Of Male Gonad Development Otic Vesicle Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Metanephric Tubule Morphogenesis Camera-type Eye Photoreceptor Cell Differentiation Male Sex Determination Maintenance Of Gastrointestinal Epithelium Otic Vesicle Development Ureter Development ERK1 And ERK2 Cascade Vitamin Transmembrane Transport Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Heart Valve Formation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Metanephric Nephron Tubule Development Regulation Of Neuron Differentiation
Tagcloud ?			aza carrier colon cpg cytosine dac deacetylase deacetylation deoxycytidine epigenetic guanine hct116 ht29 islands markedly methylation methyltransferase possessing re solute sw48 sw480 thiamine thtr2 transporter transporters trichostatin tsa
Tagcloud (Difference) ?			aza carrier colon cpg cytosine dac deacetylase deacetylation deoxycytidine epigenetic guanine hct116 ht29 islands markedly methylation methyltransferase possessing re solute sw48 sw480 thiamine thtr2 transporter transporters trichostatin tsa
Tagcloud (Intersection) ?