CDC42EP5 and SEPT7

Number of citations of the paper that reports this interaction (PMID 11584266)
38

Data Source:
HPRD (in vivo, in vitro)

		CDC42EP5	SEPT7
Gene Name		CDC42 effector protein (Rho GTPase binding) 5	septin 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Endomembrane System Membrane	Condensed Chromosome Kinetochore Stress Fiber Nucleus Nucleolus Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Apical Plasma Membrane Midbody Cleavage Furrow Axon Terminus Synapse Extracellular Vesicular Exosome
	Molecular Function	Rho GTPase Activator Activity GTP-Rho Binding	Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding
	Biological Process	JNK Cascade Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Rho GTPase Activity	Cytokinesis Mitotic Nuclear Division Regulation Of Embryonic Cell Shape Protein Heterooligomerization Cilium Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CDC42 SEPT7	11 interactors: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE REL S100A4 SEPT10 SEPT11 SEPT5 SEPT9
Entrez ID		148170	989
HPRD ID		13023	04398
Ensembl ID		ENSG00000167617
Uniprot IDs		Q6NZY7	A8K3D0 B4DNE4 Q16181
PDB IDs			2QAG 3T5D 3TW4
Enriched GO Terms of Interacting Partners?		Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cell Morphogenesis Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Regulation Of Protein Heterodimerization Activity Keratinocyte Development Regulation Of Synapse Structural Plasticity Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Golgi Localization Cell Projection Morphogenesis Cell Part Morphogenesis Filopodium Assembly Hair Follicle Placode Formation Macrophage Differentiation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Dendritic Cell Migration Cell Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Nucleus Localization Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Cell Projection Organization Regulation Of Substrate Adhesion-dependent Cell Spreading Hair Follicle Morphogenesis Epithelial Cell-cell Adhesion Substantia Nigra Development Positive Regulation Of Cytokinesis Epidermis Morphogenesis Keratinization Salivary Gland Morphogenesis Nucleus Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Development Regulation Of Filopodium Assembly Negative Regulation Of ERBB Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Cell Fate Determination Skin Morphogenesis Neural Nucleus Development Organelle Transport Along Microtubule Sprouting Angiogenesis	Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Positive Regulation Of Cell Projection Organization Rho Protein Signal Transduction Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Septin Ring Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Ras GTPase Activity Protein Complex Assembly Septin Cytoskeleton Organization Regulation Of Cellular Component Organization Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Signaling Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Mitotic Chromosome Movement Towards Spindle Pole Glomerular Visceral Epithelial Cell Migration Regulation Of Mitotic Nuclear Division Regulation Of Ras GTPase Activity Protein Heterooligomerization Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Ras Protein Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Synaptic Vesicle Targeting Positive Regulation Of GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling
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