CSTB and RAD21

Number of citations of the paper that reports this interaction (PMID 22145905)
3

Data Source:
BioGRID (two hybrid)

		CSTB	RAD21
Gene Name		cystatin B (stefin B)	RAD21 homolog (S. pombe)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleolus Cytoplasm Extracellular Vesicular Exosome	Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Meiotic Cohesin Complex
	Molecular Function	Protease Binding Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Poly(A) RNA Binding	Protein Binding
	Biological Process	Adult Locomotory Behavior Negative Regulation Of Peptidase Activity Negative Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Negative Regulation Of Proteolysis	Mitotic Cell Cycle Double-strand Break Repair DNA Recombination Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Chromosome Segregation Mitotic Nuclear Division Reciprocal Meiotic Recombination Cell Division Protein Localization To Chromatin
Pathways			Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CST3 CTSB CTSD CTSH CTSL ECT2 RAD21 SPRY2	28 interactors: CAPN1 CASP7 CFL1 COX2 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPAL WNT2B ZNF80
Entrez ID		1476	5885
HPRD ID		03091	05924
Ensembl ID			ENSG00000164754
Uniprot IDs		P04080 Q76LA1	O60216
PDB IDs		1STF 2OCT
Enriched GO Terms of Interacting Partners?		Cellular Response To Thyroid Hormone Stimulus Response To Thyroid Hormone Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Antigen Processing And Presentation Epithelial Tube Branching Involved In Lung Morphogenesis Cellular Response To Organic Substance Apoptotic Process Programmed Cell Death Lung Morphogenesis Cell Death Death Negative Regulation Of Elastin Catabolic Process Negative Regulation Of Blood Vessel Remodeling Negative Regulation Of Collagen Catabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Immune Response-regulating Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Catalytic Activity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Response To Organic Substance Toll-like Receptor Signaling Pathway Neuropeptide Catabolic Process Macrophage Apoptotic Process Cellular Response To Hormone Stimulus Regulation Of Apoptotic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteolysis Regulation Of Collagen Catabolic Process Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Activation Of Innate Immune Response Regulation Of Cell Death Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Innate Immune Response Catabolic Process Bradykinin Catabolic Process Regulation Of Blood Vessel Remodeling Branching Morphogenesis Of An Epithelial Tube Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Immune Response Response To Stress Regulation Of Cellular Protein Metabolic Process Myeloid Cell Apoptotic Process	Cell Division Mitotic Nuclear Division Cellular Protein Localization Viral Life Cycle Cytoskeleton Organization Mitotic Cell Cycle Process Negative Regulation Of DNA Endoreduplication Protein Localization To Endoplasmic Reticulum Cell Cycle Process Mitotic Cell Cycle Organelle Organization Protein Localization To Organelle Negative Regulation Of DNA Replication MRNA Metabolic Process Viral Process Protein Localization Cellular Localization Cellular Protein Complex Disassembly Regulation Of DNA Endoreduplication Protein Complex Disassembly Cell Cycle Negative Regulation Of Cell Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Cell Polarity Negative Regulation Of DNA Metabolic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of DNA Replication Sister Chromatid Cohesion Establishment Of Mitotic Spindle Orientation Actin Cytoskeleton Organization Translational Termination Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Protein Localization To Organelle Nuclear-transcribed MRNA Catabolic Process Actin Filament-based Process MRNA Catabolic Process Protein Targeting To Membrane Establishment Or Maintenance Of Cell Polarity Viral Entry Into Host Cell Translational Elongation Spindle Localization Regulation Of Metabolic Process Entry Into Host Cell RNA Catabolic Process Positive Regulation Of Translational Initiation In Response To Stress
Tagcloud ?		ataxia cerebella cerebellar cerebellum compatible connected cystatin electrophysiological epm1 gabaa gabaergic granule hyperexcitable implies interneurons lundborg manifesting myoclonus neuroinflammation p30 p7 pathogenetic pinpointed precedes purkinje recessively recordings terminals unverricht	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Difference) ?		ataxia cerebella cerebellar cerebellum compatible connected cystatin electrophysiological epm1 gabaa gabaergic granule hyperexcitable implies interneurons lundborg manifesting myoclonus neuroinflammation p30 p7 pathogenetic pinpointed precedes purkinje recessively recordings terminals unverricht	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger
Tagcloud (Intersection) ?