PRR35 and HPCA

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		PRR35	HPCA
Name		proline rich 35	hippocalcin
Structure		No pdb structure
GO Annotations	Cellular Component	None	Cytoplasm Cytosol Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	None	Regulation Of Signal Transduction Calcium-mediated Signaling Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Response To Aroclor 1254 Cellular Response To L-glutamate
GWAS		L1-L4 bone mineral density x serum urate levels interaction ( 34046847 )	Daytime nap ( 33568662 )
Novel Interactors		None recorded	12 novel interactors: APC BMP8B CSF3R DPYD E2F2 NDC80 NUDC RAE1 RUNX3 TMEM54 TNFRSF8 TUBA4A
Interacting Genes		80 interacting genes: ABHD11 ACTMAP ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 CARD10 CCDC136 CFAP68 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655	17 interacting genes: AP2B1 C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2
Entrez ID		146325	3208
HPRD ID		10046	00811
Ensembl ID		ENSG00000161992	ENSG00000121905
Uniprot IDs		P0CG20	P84074
PDB IDs		Not available	5G4P 5G58 5M6C 7OWM
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament	Phosphocreatine Biosynthetic Process Creatine Kinase Activity