HPCA and NMT1

Number of citations: 0 (PubMedID 8360179)
Data Source: HPRD (in vitro)

		HPCA	NMT1
Name		hippocalcin	N-myristoyltransferase 1
Structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Postsynapse Glutamatergic Synapse	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity Myristoyltransferase Activity
	Biological Process	Regulation Of Signal Transduction Calcium-mediated Signaling Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Response To Aroclor 1254 Cellular Response To L-glutamate	In Utero Embryonic Development N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Cellular Response To Nutrient Levels Ketone Metabolic Process Protein Localization To Membrane Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of TORC1 Signaling
Pathways		None	Late Phase of HIV Life Cycle eNOS activation Inactivation, recovery and regulation of the phototransduction cascade Activation, myristolyation of BID and translocation to mitochondria
Drugs		None	(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone
GWAS		Daytime nap ( 33568662 )	Asthma ( 31619474 ) Blood glucose levels ( 31928498 ) Brain morphology (MOSTest) ( 32665545 ) Craniofacial microsomia ( 26853712 ) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Multisite chronic pain ( 31194737 33830993 ) Periventricular white matter hyperintensities ( 32517579 ) Plateletcrit ( 32888494 ) Pulse pressure ( 30578418 ) Systolic blood pressure ( 31928498 30578418 ) Walking pace ( 33128006 ) White matter hyperintensities ( 32358547 ) White matter hyperintensity volume ( 33293549 )
Interacting Genes		17 interacting genes: AP2B1 C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2	14 interacting genes: ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53
Entrez ID		3208	4836
HPRD ID		00811	01187
Ensembl ID		ENSG00000121905	ENSG00000136448
Uniprot IDs		P84074	P30419
PDB IDs		5G4P 5G58 5M6C 7OWM	1RXT 3IU1 3IU2 3IWE 3JTK 4C2Y 4C2Z 5MU6 5NPQ 5O6H 5O6J 5O9S 5O9T 5O9U 5O9V 5UUT 6EHJ 6F56 6FZ2 6FZ3 6FZ5 6PAV 6QRM 6SJZ 6SK2 6SK3 6SK8 6SKJ 7OWM 7OWN 7OWO 7OWP 7OWQ 7OWR 7OWU 7RK3 8Q23 8Q24 8Q26 8Q2Z 8Q3D 8Q3S 8Q3T
GO Terms Enriched among Interactors		Phosphocreatine Biosynthetic Process Creatine Kinase Activity	Membrane Raft Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Stimulatory C-type Lectin Receptor Signaling Pathway Scaffold Protein Binding Cellular Response To Lectin Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Regulation Of Cellular Localization Response To Amino Acid Negative Regulation Of Inflammatory Response To Antigenic Stimulus Fc-gamma Receptor Signaling Pathway Regulation Of Protein Localization Response To Fluid Shear Stress Non-membrane Spanning Protein Tyrosine Kinase Activity T Cell Costimulation Regulation Of Transport Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Apoptotic Signaling Pathway Enzyme Binding Fc Receptor Signaling Pathway Signaling Receptor Activator Activity Cellular Response To L-glutamate Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Phospholipase Activator Activity Cellular Response To Amino Acid Stimulus Cellular Response To Oxygen-containing Compound Positive Regulation Of Protein Localization To Membrane Regulation Of Establishment Of Protein Localization Regulation Of Apoptotic Process Plasma Membrane Regulation Of Programmed Cell Death Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Response To Hydrogen Peroxide DNA Damage Checkpoint Signaling Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasm Negative Regulation Of Cell Communication Negative Regulation Of Signaling Autophagy Calcium Ion Binding Perinuclear Endoplasmic Reticulum Cellular Response To Stress Response To L-glutamate Lymphocyte Proliferation Mononuclear Cell Proliferation Negative Regulation Of Protein Transport Phospholipase Binding Cellular Response To Platelet-derived Growth Factor Stimulus