CRYGC and MIP

Number of citations of the paper that reports this interaction (PubMedID 18004741)
0

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CRYGC	MIP
Description		crystallin gamma C	major intrinsic protein of lens fiber
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Membrane Apical Plasma Membrane Anchoring Junction
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity Channel Activity Cell Adhesion Mediator Activity
	Biological Process	Lens Development In Camera-type Eye Visual Perception	Lens Development In Camera-type Eye Water Transport Visual Perception Homotypic Cell-cell Adhesion Maintenance Of Lens Transparency Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways			Passive transport by Aquaporins
Drugs			B-nonylglucoside
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)	Axial length ( 24144296) Lipoprotein (a) levels ( 33730874) Serum metabolite levels ( 33031748)
Interacting Genes		8 interacting genes: CRYAA CRYAB CRYBB2 CRYGD HSPB1 HSPB2 MIP TRIM7	48 interacting genes: AQP6 AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1
Entrez ID		1420	4284
HPRD ID		00435	01098
Ensembl ID		ENSG00000163254	ENSG00000135517
Uniprot IDs		A0A0X8GLL6 P07315	P30301
PDB IDs		2NBR
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye Protein Refolding Response To Heat Unfolded Protein Binding Response To Temperature Stimulus Visual Perception Sensory Perception Of Light Stimulus Protein Folding Camera-type Eye Development Tubulin Complex Assembly Contractile Muscle Fiber Eye Development Sensory Perception Response To Reactive Oxygen Species Apoptotic Process Involved In Morphogenesis Sensory Organ Development Structural Molecule Activity Apoptotic Process Involved In Development System Process Negative Regulation Of Intracellular Transport Negative Regulation Of Apoptotic Process Homotypic Cell-cell Adhesion Nervous System Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Protein Kinase C Signaling Response To Oxidative Stress Response To Unfolded Protein Response To Stress Response To Hydrogen Peroxide Protein Kinase C Inhibitor Activity Z Disc Muscle Structure Development Somatic Muscle Development Regulation Of Protein Kinase C Signaling Regulation Of Apoptotic Process Gap Junction-mediated Intercellular Transport Regulation Of Programmed Cell Death Lens Fiber Cell Morphogenesis Cardiac Myofibril Maintenance Of Lens Transparency Actin Filament Bundle Anterograde Axonal Protein Transport Intercellular Transport Microtubule-based Process Protein Stabilization Identical Protein Binding Cell Adhesion Mediator Activity Response To UV-A Regulation Of Intracellular Transport	Membrane Lens Development In Camera-type Eye Structural Constituent Of Eye Lens Structural Molecule Activity Urea Channel Activity Gap Junction Channel Activity Connexin Complex SNARE Binding Synaptic Vesicle Membrane One-carbon Compound Transport Water Transport Gap Junction Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Clathrin-sculpted Monoamine Transport Vesicle Membrane Urea Transmembrane Transporter Activity Membrane Docking Camera-type Eye Development Gap Junction-mediated Intercellular Transport Fluid Transport Plasma Membrane Protein Binding Regulation Of Calcium Ion-dependent Exocytosis Chromaffin Granule Membrane Urea Transmembrane Transport Tubulin Complex Assembly Intercellular Transport Amine Transport Urea Transport Modulation Of Chemical Synaptic Transmission Eye Development Positive Regulation Of Catecholamine Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion Water Channel Activity Calcium Channel Inhibitor Activity Vesicle Docking Detection Of Calcium Ion Positive Regulation Of Calcium Ion-dependent Exocytosis Dense Core Granule Calcium Ion Sensor Activity Voltage-gated Potassium Channel Complex Sensory Organ Development Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Dendrite Extension Positive Regulation Of Vesicle Fusion Glutathione Peroxidase Activity
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