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ASB8 and MCM7
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
ASB8
MCM7
Description
ankyrin repeat and SOCS box containing 8
minichromosome maintenance complex component 7
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Membrane
MCM Complex
CMG Complex
Molecular Function
Protein Binding
Nucleotide Binding
DNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Single-stranded DNA Helicase Activity
Biological Process
Protein Ubiquitination
Intracellular Signal Transduction
Double-strand Break Repair Via Break-induced Replication
DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
DNA Damage Response
Cell Population Proliferation
Response To Xenobiotic Stimulus
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Phosphorylation
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Xenobiotic Stimulus
Pathways
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Activation of ATR in response to replication stress
Unwinding of DNA
Assembly of the pre-replicative complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
7 interacting genes:
ELOB
HOXD4
MCM7
MYCBP2
RCN1
RIN3
SERTAD1
79 interacting genes:
ABI2
AK8
APP
ASB8
C8orf34
CCDC102B
CCND1
CCNH
CDC42
CDC45
CDC6
CDC7
CDK7
CDKN1B
CEBPA
CEP68
CHEK1
COG6
CRLS1
CRYAA
DBF4
DNAAF6
DUX4
ELOC
ESCO2
FHL2
GOLGA2
H3-4
HIF1A
IKBKG
IKZF3
INTS6
KIFC3
LINC01554
LNX2
LRR1
MAGEA6
MBIP
MCM10
MCM2
MCM3
MCM4
MCM5
MCM6
MCM8
MEOX2
MIPOL1
MNAT1
NAB2
NFKBIA
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
PLK1
PNMA1
RAD17
RB1
RBL1
RBL2
RBM8A
RBPMS
RINT1
RNF181
RPA1
SMC1A
SNTA1
SP2
SSX2IP
TFIP11
TREX1
TRIM27
TRIM54
TRIM63
UBE3A
UBQLN1
USHBP1
Entrez ID
140461
4176
HPRD ID
10675
01154
Ensembl ID
ENSG00000177981
ENSG00000166508
Uniprot IDs
F5GYF0
Q9H765
A0A0S2Z4A5
C6EMX8
C9J8M6
P33993
PDB IDs
6XTX
6XTY
7PFO
7PLO
7W1Y
7W68
8B9D
8RWV
8S09
8S0A
8S0B
8S0D
8S0E
8S0F
8W0E
8W0F
8W0G
8W0I
9CAQ
Enriched GO Terms of Interacting Partners
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DNA Replication Initiation
DNA Replication
DNA Replication Origin Binding
DNA Metabolic Process
Nuclear Origin Of Replication Recognition Complex
Chromosome, Telomeric Region
Nucleoplasm
Regulation Of DNA Replication
Origin Recognition Complex
Double-strand Break Repair Via Break-induced Replication
Nucleus
DNA Damage Response
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
CMG Complex
MCM Complex
Regulation Of Mitotic Cell Cycle
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleic Acid Metabolic Process
Negative Regulation Of Cell Cycle
Single-stranded DNA Binding
Regulation Of Cell Cycle Process
DNA Repair
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Negative Regulation Of Cell Cycle Process
Negative Regulation Of Cell Cycle Phase Transition
Double-strand Break Repair Via Homologous Recombination
Regulation Of DNA Metabolic Process
Cellular Response To Stress
Recombinational Repair
Mitotic DNA Integrity Checkpoint Signaling
Chromosome
Nucleobase-containing Compound Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Double-strand Break Repair
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cell Cycle G1/S Phase Transition
DNA Recombination
Single-stranded DNA Helicase Activity
Regulation Of Primary Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Transcription Factor TFIIK Complex
Mitotic G2/M Transition Checkpoint
CAK-ERCC2 Complex
Mitotic DNA Replication Initiation
Regulation Of Lipid Kinase Activity
Macromolecule Metabolic Process
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