RNF113B and UBE2R2

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		RNF113B	UBE2R2
Gene Name		ring finger protein 113B	ubiquitin-conjugating enzyme E2R 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function	Zinc Ion Binding	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process		Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: UBE2H UBE2L3 UBE2R2 UBE2U	17 interactors: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 DTX3L DZIP3 FBXW5 INF2 MEOX1 PNPLA2 RBX1 RNF113B UBA1 UBC
Entrez ID		140432	54926
HPRD ID		15745	15602
Ensembl ID		ENSG00000139797	ENSG00000107341
Uniprot IDs		Q8IZP6	Q712K3
PDB IDs		2CSY
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K11-linked Ubiquitination Protein K48-linked Ubiquitination Proteolysis Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Protein Metabolic Process Histone Ubiquitination Protein Monoubiquitination Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Metabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of ERBB Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Wnt Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Wnt Signaling Pathway Rhythmic Process
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