CPB2 and TINAG

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CPB2	TINAG
Gene Name		carboxypeptidase B2 (plasma)	tubulointerstitial nephritis antigen
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome	Basement Membrane
	Molecular Function	Metallocarboxypeptidase Activity Zinc Ion Binding	Nucleotide Binding Cysteine-type Endopeptidase Activity Scavenger Receptor Activity Polysaccharide Binding
	Biological Process	Positive Regulation Of Extracellular Matrix Constituent Secretion Proteolysis Blood Coagulation Response To Heat Negative Regulation Of Plasminogen Activation Response To Drug Fibrinolysis Negative Regulation Of Fibrinolysis Cellular Response To Glucose Stimulus Liver Regeneration Negative Regulation Of Hepatocyte Proliferation	Proteolysis Receptor-mediated Endocytosis Immune Response Cell Adhesion
Pathways		Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins
Drugs
Diseases
GWAS			Radiation response ( 20923822)
Protein-Protein Interactions		7 interactors: A2M C5 F2 PLG PZP TINAG UBC	3 interactors: CPB2 TERF1 TMEM45B
Entrez ID		1361	27283
HPRD ID		04374	09483
Ensembl ID		ENSG00000080618	ENSG00000137251
Uniprot IDs		Q96IY4	Q6NSC1 Q9UJW2
PDB IDs		3D66 3D67 3D68 3LMS
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Negative Regulation Of Fibrinolysis Regulation Of Fibrinolysis Blood Coagulation, Intrinsic Pathway Protein Activation Cascade Platelet Activation Leukocyte Migration Fibrinolysis Positive Regulation Of Blood Coagulation Negative Regulation Of Catalytic Activity Regulation Of Complement Activation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Positive Regulation Of Coagulation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Wound Healing Regulation Of Humoral Immune Response Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Blood Coagulation Immune System Process Regulation Of Protein Metabolic Process Negative Regulation Of Coagulation Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Negative Regulation Of Wound Healing Regulation Of Peptidase Activity Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Acute Inflammatory Response Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Extracellular Matrix Disassembly Regulation Of Blood Coagulation Regulation Of Body Fluid Levels Proteolysis Wound Healing Negative Regulation Of Macrophage Chemotaxis Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Wound Healing Activation Of MAPK Activity Cell Activation Response To Wounding Cellular Homeostasis Mononuclear Cell Migration Regulation Of Intracellular Signal Transduction	Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Extracellular Matrix Constituent Secretion Negative Regulation Of Protein Processing Regulation Of Protein Processing Telomere Maintenance Via Telomere Shortening Negative Regulation Of Hepatocyte Proliferation Liver Regeneration Negative Regulation Of Telomere Maintenance Via Telomerase Response To Drug Negative Regulation Of Plasminogen Activation Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Fibrinolysis Regulation Of Telomere Maintenance Via Telomerase Regulation Of Hepatocyte Proliferation Positive Regulation Of Microtubule Polymerization Regulation Of Fibrinolysis Regulation Of Telomerase Activity Negative Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Fibrinolysis Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Blood Coagulation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Extracellular Matrix Organization Mitotic Spindle Checkpoint Positive Regulation Of Coagulation Positive Regulation Of Mitotic Nuclear Division Homeostatic Process Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Wound Healing Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Cellular Response To Glucose Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		3t3 authentic binds block bovine cap cdcl2 complementation defect demonstrates eukaryotic influenza inserted m7gpppnm metallothionein mrnas mt nih papilloma produces product recognizes recombinant relieves strand transfection vector viral	4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Difference) ?		3t3 authentic binds block bovine cap cdcl2 complementation defect demonstrates eukaryotic influenza inserted m7gpppnm metallothionein mrnas mt nih papilloma produces product recognizes recombinant relieves strand transfection vector viral	4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Intersection) ?