TINAG and TMEM45B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TINAG	TMEM45B
Gene Name		tubulointerstitial nephritis antigen	transmembrane protein 45B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane	Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Cysteine-type Endopeptidase Activity Scavenger Receptor Activity Polysaccharide Binding
	Biological Process	Proteolysis Receptor-mediated Endocytosis Immune Response Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Radiation response ( 20923822)	Breast cancer ( 22383897) Obesity-related traits ( 23251661) Type 2 diabetes ( 22238593)
Protein-Protein Interactions		3 interactors: CPB2 TERF1 TMEM45B	3 interactors: TINAG UBE2G2 VKORC1
Entrez ID		27283	120224
HPRD ID		09483	14020
Ensembl ID		ENSG00000137251	ENSG00000151715
Uniprot IDs		Q6NSC1 Q9UJW2	Q96B21
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Extracellular Matrix Constituent Secretion Negative Regulation Of Protein Processing Regulation Of Protein Processing Telomere Maintenance Via Telomere Shortening Negative Regulation Of Hepatocyte Proliferation Liver Regeneration Negative Regulation Of Telomere Maintenance Via Telomerase Response To Drug Negative Regulation Of Plasminogen Activation Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Fibrinolysis Regulation Of Telomere Maintenance Via Telomerase Regulation Of Hepatocyte Proliferation Positive Regulation Of Microtubule Polymerization Regulation Of Fibrinolysis Regulation Of Telomerase Activity Negative Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Fibrinolysis Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Blood Coagulation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Extracellular Matrix Organization Mitotic Spindle Checkpoint Positive Regulation Of Coagulation Positive Regulation Of Mitotic Nuclear Division Homeostatic Process Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Wound Healing Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Cellular Response To Glucose Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Vitamin K Metabolic Process Peptidyl-glutamic Acid Carboxylation Peptidyl-amino Acid Modification Protein K48-linked Ubiquitination Quinone Metabolic Process Drug Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Difference) ?		4alpha actinin albuminuria alpha3 amelioration aquaporin chelator diabetic dismutase dn epoxide hsp hydrolase itraq kidneys nephritis nephropathy normalized oxphos podocyte reversal streptozotocin teta triethylenetetramine tubulointerstitial vdac vdac1 vdac2 vialpha1
Tagcloud (Intersection) ?