COPA and COPZ1

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (pull down, biochemical, biochemical)

		COPA	COPZ1
Gene Name		coatomer protein complex, subunit alpha	coatomer protein complex, subunit zeta 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane COPI Vesicle Coat Extracellular Vesicular Exosome	Cytosol COPI Vesicle Coat
	Molecular Function	Hormone Activity Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Pancreatic Juice Secretion COPI Coating Of Golgi Vesicle Membrane Organization	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Mean platelet volume ( 22139419) Platelet counts ( 23263863)
Protein-Protein Interactions		12 interactors: ARCN1 ARFGAP1 COPB2 COPE COPZ1 MTNR1B PDGFRB SACM1L SLC25A11 STX8 TMED10 TMED2	7 interactors: APP COPA COPG1 COPG2 TMED10 TMED9 UGT1A1
Entrez ID		1314	22818
HPRD ID		03564	16738
Ensembl ID		ENSG00000122218	ENSG00000111481
Uniprot IDs		P53621	B4DDX8 F8VS17 F8VWL5 P61923
PDB IDs			2HF6
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Organelle Organization Intra-Golgi Vesicle-mediated Transport Cellular Localization Cargo Loading Into Vesicle ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating COPII-coated Vesicle Budding Transport Cytoplasmic Transport Cell Migration Involved In Coronary Angiogenesis Cerebellar Purkinje Cell Layer Maturation Metanephric Mesenchymal Cell Migration Golgi Organization Angiogenesis Involved In Coronary Vascular Morphogenesis Cell Migration Involved In Kidney Development Alpha-ketoglutarate Transport Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Smooth Muscle Cell Chemotaxis Cerebellum Maturation Metanephric Comma-shaped Body Morphogenesis Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Cell Migration Involved In Vasculogenesis Metanephric S-shaped Body Morphogenesis Glomerular Mesangial Cell Proliferation Positive Regulation Of Metanephric Mesenchymal Cell Migration Comma-shaped Body Morphogenesis	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Golgi Vesicle Transport Membrane Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle-mediated Transport Intracellular Transport Establishment Of Organelle Localization Establishment Of Localization In Cell Organelle Localization Cellular Localization Membrane Organization Intracellular Protein Transport Golgi Organization Biphenyl Catabolic Process Bilirubin Conjugation Cellular Protein Localization Protein Transport Establishment Of Protein Localization Transport Digestion Synaptic Growth At Neuromuscular Junction Secretion Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Glucuronidation Protein Localization Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Flavone Metabolic Process Axon Choice Point Recognition Establishment Of Golgi Localization Pancreatic Juice Secretion Heme Catabolic Process Steroid Metabolic Process Xenobiotic Glucuronidation Cargo Loading Into Vesicle Neuron Remodeling Cellular Response To Ethanol Biphenyl Metabolic Process Xenobiotic Catabolic Process
Tagcloud ?		atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	atpases cgr cognate copa copb copper copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		atpases cgr cognate copa copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur