COPZ1 and TMED10

Number of citations of the paper that reports this interaction (PMID 9472029)
82

Data Source:
BioGRID (unspecified method)

		COPZ1	TMED10
Gene Name		coatomer protein complex, subunit zeta 1	transmembrane emp24-like trafficking protein 10 (yeast)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol COPI Vesicle Coat	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome Gamma-secretase Complex
	Molecular Function		Protein Binding Syntaxin Binding Protein Complex Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Membrane Organization	Kidney Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Cargo Loading Into Vesicle COPI-coated Vesicle Budding Response To Alkaloid Regulated Secretory Pathway Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Protein Oligomerization Regulation Of Beta-amyloid Formation
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419) Platelet counts ( 23263863)	Height ( 19343178)
Protein-Protein Interactions		7 interactors: APP COPA COPG1 COPG2 TMED10 TMED9 UGT1A1	15 interactors: APH1A ARCN1 ARF1 COPA COPB1 COPB2 COPE COPG1 COPZ1 DHODH GORASP2 NCSTN PSENEN SEC23B TMED2
Entrez ID		22818	10972
HPRD ID		16738	12013
Ensembl ID		ENSG00000111481	ENSG00000170348
Uniprot IDs		B4DDX8 F8VS17 F8VWL5 P61923	B4DL12 P49755
PDB IDs		2HF6
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Golgi Vesicle Transport Membrane Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle-mediated Transport Intracellular Transport Establishment Of Organelle Localization Establishment Of Localization In Cell Organelle Localization Cellular Localization Membrane Organization Intracellular Protein Transport Golgi Organization Biphenyl Catabolic Process Bilirubin Conjugation Cellular Protein Localization Protein Transport Establishment Of Protein Localization Transport Digestion Synaptic Growth At Neuromuscular Junction Secretion Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Glucuronidation Protein Localization Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Flavone Metabolic Process Axon Choice Point Recognition Establishment Of Golgi Localization Pancreatic Juice Secretion Heme Catabolic Process Steroid Metabolic Process Xenobiotic Glucuronidation Cargo Loading Into Vesicle Neuron Remodeling Cellular Response To Ethanol Biphenyl Metabolic Process Xenobiotic Catabolic Process	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Protein Localization Intra-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Amyloid Precursor Protein Catabolic Process Membrane Protein Intracellular Domain Proteolysis Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Cellular Localization Notch Receptor Processing Cellular Protein Localization Membrane Protein Proteolysis Organelle Organization Transport Ephrin Receptor Signaling Pathway ER To Golgi Vesicle-mediated Transport Notch Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Protein Processing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cerebellar Purkinje Cell Layer Maturation Apoptotic Signaling Pathway Axon Guidance Cerebellum Maturation 'de Novo' UMP Biosynthetic Process Body Fluid Secretion Axonogenesis Establishment Of Golgi Localization
Tagcloud ?		atpases cgr cognate copa copb copper copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Difference) ?		atpases cgr cognate copa copb copper copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Intersection) ?