COL8A2

Gene Name		collagen, type VIII, alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding, Bridging
	Biological Process	Angiogenesis Single Organismal Cell-cell Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Camera-type Eye Morphogenesis Epithelial Cell Proliferation
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Corneal structure ( 23291589)
Protein-protein Interactions		2 interactors: COL8A1 SGTA
Entrez ID		1296
HPRD ID		08347
Ensembl ID		ENSG00000171812
Uniprot IDs		E9PP49 P25067
PDB IDs
Enriched GO Terms of Interacting Partners?		Endodermal Cell Differentiation Endoderm Formation Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Epithelial Cell Proliferation Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Positive Regulation Of Cell-substrate Adhesion Camera-type Eye Morphogenesis Formation Of Primary Germ Layer
Tagcloud ?		acetylcysteine bl6 blotting c57 celltiter chop confocal corneal drinking dystrophy endothelial endothelium fecd fuchs glo grp78 h2o2 homozygous ingestion inos knock l450w luminescent nac polymegathism reagent thapsigargin unfolded untreated