CTD and GTF2H1

Number of citations of the paper that reports this interaction (PMID 8934526)
86

Data Source:
BioGRID (enzymatic study)

		CTD	GTF2H1
Gene Name		Coats disease	general transcription factor IIH, polypeptide 1, 62kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Core TFIIH Complex Nucleoplasm Holo TFIIH Complex
	Molecular Function		Protein Kinase Activity Protein Binding DNA-dependent ATPase Activity RNA Polymerase II Carboxy-terminal Domain Kinase Activity
	Biological Process		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Nucleotide-excision Repair, DNA Damage Removal DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Protein Phosphorylation Gene Expression Viral Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			RNA Polymerase II Promoter Escape Formation of HIV-1 elongation complex containing HIV-1 Tat Nucleotide Excision Repair RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Chain Elongation RNA Polymerase II Transcription RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Formation of transcription-coupled NER (TC-NER) repair complex RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER NoRC negatively regulates rRNA expression HIV Transcription Initiation HIV Life Cycle RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation Dual incision reaction in GG-NER mRNA Capping RNA Polymerase I Transcription RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Global Genomic NER (GG-NER) RNA Polymerase II Transcription Initiation And Promoter Clearance Transcription-coupled NER (TC-NER) Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of incision complex in GG-NER RNA Polymerase II Transcription Initiation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Schizophrenia ( 23212062)	Amyloid A Levels ( 21124955) Pancreatic cancer ( 23180869)
Protein-Protein Interactions		13 interactors: CCNC CCNH CCNT1 CDK7 CDK8 CDK9 CPSF1 GTF2H1 MNAT1 POLR2A TBP TTK WAC	42 interactors: ACTN1 AR ATF7IP BRPF1 CCNH CCSER2 CDK7 CTD E2F1 ERCC2 ERCC3 ERCC4 ERCC5 ESR1 FUBP1 GTF2E1 GTF2E2 GTF2H2 GTF2H3 HNF4A HNRNPU HOXC11 JDP2 KIF13A KPNA3 MCM2 MMS19 PIK3R1 PLCG1 POU2AF1 PSMC2 RAD23A REEP5 RXRB TNIP1 TP53 TRIOBP TXNRD2 USHBP1 XPA XPC ZSCAN1
Entrez ID		1283	2965
HPRD ID			01807
Ensembl ID			ENSG00000110768
Uniprot IDs			P32780
PDB IDs			1PFJ 2DII 2RNR
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Viral Transcription Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Process DNA-templated Transcription, Termination Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression 7-methylguanosine RNA Capping Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Viral Process Regulation Of Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Negative Regulation Of Gene Expression, Epigenetic RNA Metabolic Process Nucleotide-excision Repair Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression, Epigenetic Protein Phosphorylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To DNA Damage Stimulus MRNA Metabolic Process Regulation Of Protein Metabolic Process Nitrogen Compound Metabolic Process RNA Processing	Nucleotide-excision Repair, DNA Damage Removal Nucleotide-excision Repair Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription-coupled Nucleotide-excision Repair Viral Process Cellular Response To DNA Damage Stimulus Transcription From RNA Polymerase II Promoter DNA Catabolic Process Transcription Elongation From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Response To UV Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Termination Of RNA Polymerase I Transcription Gene Expression Transcription Elongation From RNA Polymerase I Promoter Nitrogen Compound Metabolic Process DNA Repair Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Positive Regulation Of Viral Process DNA Metabolic Process RNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription Regulation Of Viral Process Nucleotide-excision Repair, DNA Incision Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Viral Transcription Response To Stress
Tagcloud ?		ana anas antinuclear assayed awaited connective discordant discrimination dsdna elisa elisas erythematosus fana gives immunosorbent jo labor lupus mana mesacup personnel rnp sera ss ssdna subjective suitable trained uses
Tagcloud (Difference) ?		ana anas antinuclear assayed awaited connective discordant discrimination dsdna elisa elisas erythematosus fana gives immunosorbent jo labor lupus mana mesacup personnel rnp sera ss ssdna subjective suitable trained uses
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