UBXN10 and TRAF3IP1

Number of citations of the paper that reports this interaction (PubMedID 26389662)
53

Data Source:
BioGRID (pull down)

		UBXN10	TRAF3IP1
Description		UBX domain protein 10	TRAF3 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cilium Intraciliary Transport Particle B Cell Projection	Fibrillar Center Nucleoplasm Cytoplasm Centrosome Cytoskeleton Cilium Axoneme Nuclear Body Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Tip Ciliary Base
	Molecular Function	Protein Binding Ubiquitin Binding	Protein Binding Microtubule Binding
	Biological Process	Cell Projection Organization ERAD Pathway Cilium Assembly	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Neural Tube Patterning Cell Projection Organization Embryonic Camera-type Eye Development Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Intraciliary Anterograde Transport Post-anal Tail Morphogenesis Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Animal Organ Development System Development Negative Regulation Of Defense Response To Virus Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		13 interacting genes: APP CLUAP1 IFT46 IFT57 IFT70A IFT70B IFT80 LRRK2 PRMT6 TRAF3IP1 UBXN6 UNC13A VCP	31 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT ITSN1 MACF1 OLFM1 PCNT SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		127733	26146
HPRD ID		18255	09571
Ensembl ID		ENSG00000162543	ENSG00000204104
Uniprot IDs		Q96LJ8	Q8TDR0
PDB IDs			2EQO 8KCQ
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Particle B Intraciliary Anterograde Transport Intraciliary Transport Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Ciliary Tip Microtubule-based Transport Establishment Of Localization In Cell Intracellular Transport Microtubule-based Movement Cellular Localization Microtubule-based Process Cell Projection Cell Projection Organization Cilium Assembly Cilium Organization Ciliary Basal Body Cilium Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Smoothened Signaling Pathway Cellular Component Assembly Plasma Membrane Bounded Cell Projection Organization Intraciliary Transport Particle B Binding Centrosome Ciliary Base Organelle Assembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Cellular Response To Manganese Ion Left/right Pattern Formation Response To Manganese Ion Microtubule Organizing Center Golgi-associated Vesicle Regulation Of Wnt Signaling Pathway Cellular Response To Catecholamine Stimulus Syntaxin-1 Binding Response To Catecholamine Negative Regulation Of Keratinocyte Proliferation Regulation Of Proteolysis Organelle Organization Keratinocyte Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of ATP Metabolic Process Anatomical Structure Morphogenesis Terminal Bouton Cytoskeleton Endosome Transport Via Multivesicular Body Sorting Pathway	Golgi To Plasma Membrane Transport Post-Golgi Vesicle-mediated Transport Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Postsynapse Organization Organelle Organization Regulation Of Neuron Projection Development Positive Regulation Of Axonogenesis Axo-dendritic Transport Regulation Of Axon Extension Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Cellular Component Organization Positive Regulation Of Cell Projection Organization Golgi To Plasma Membrane Protein Transport Cytoskeleton Organization Positive Regulation Of Axon Extension Meiotic Chromosome Condensation Establishment Of Protein Localization Condensin Complex Positive Regulation Of Chromosome Condensation Cilium Assembly Positive Regulation Of Cell Differentiation Regulation Of Axonogenesis Golgi Vesicle Transport Regulation Of Dendritic Spine Development Dendritic Spine Establishment Of Protein Localization To Plasma Membrane Vesicle-mediated Transport Cilium Organization CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Synapse Organization Axon Cytoplasm Axonal Transport Cellular Localization Organelle Assembly Regulation Of Developmental Growth Transport Along Microtubule Clathrin-coated Pit MyD88-independent Toll-like Receptor Signaling Pathway Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Endosome Molecular Adaptor Activity Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Developmental Process Plasma Membrane Bounded Cell Projection Assembly Signaling Adaptor Activity Mitotic Chromosome Condensation
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